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Suzuki-Miyaura approach to JNJ-26076713, an orally active tetrahydroquinoline-containing alphaVbeta3/alphaVbeta5 integrin antagonist. enantioselective synthesis and stereochemical studies.
Kinney WA, Teleha CA, Thompson AS, Newport M, Hansen R, Ballentine S, Ghosh S, Mahan A, Grasa G, Zanotti-Gerosa A, Dingenen J, Schubert C, Zhou Y, Leo GC, McComsey DF, Santulli RJ, Maryanoff BE. Kinney WA, et al. Among authors: grasa g. J Org Chem. 2008 Mar 21;73(6):2302-10. doi: 10.1021/jo702551t. Epub 2008 Feb 16. J Org Chem. 2008. PMID: 18278942
Synthesis and X-ray structure determination of highly active Pd(II), Pd(I), and Pd(0) complexes of di(tert-butyl)neopentylphosphine (DTBNpP) in the arylation of amines and ketones.
Hill LL, Crowell JL, Tutwiler SL, Massie NL, Hines CC, Griffin ST, Rogers RD, Shaughnessy KH, Grasa GA, Johansson Seechurn CC, Li H, Colacot TJ, Chou J, Woltermann CJ. Hill LL, et al. Among authors: grasa ga. J Org Chem. 2010 Oct 1;75(19):6477-88. doi: 10.1021/jo101187q. J Org Chem. 2010. PMID: 20806983
19 results