Gallagher JT - Search Results

1

Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms.

Goodger SJ, Robinson CJ, Murphy KJ, Gasiunas N, Harmer NJ, Blundell TL, Pye DA, Gallagher JT. Goodger SJ, et al. Among authors: gallagher jt. J Biol Chem. 2008 May 9;283(19):13001-8. doi: 10.1074/jbc.M704531200. Epub 2008 Feb 14. J Biol Chem. 2008. PMID: 18281281 Free article.

2

Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes.

Robinson CJ, Harmer NJ, Goodger SJ, Blundell TL, Gallagher JT. Robinson CJ, et al. Among authors: gallagher jt. J Biol Chem. 2005 Dec 23;280(51):42274-82. doi: 10.1074/jbc.M505720200. Epub 2005 Oct 11. J Biol Chem. 2005. PMID: 16219767 Free article.

3

VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase.

Robinson CJ, Mulloy B, Gallagher JT, Stringer SE. Robinson CJ, et al. Among authors: gallagher jt. J Biol Chem. 2006 Jan 20;281(3):1731-40. doi: 10.1074/jbc.M510760200. Epub 2005 Oct 28. J Biol Chem. 2006. PMID: 16258170 Free article.

4

Heparin sequencing.

Stringer SE, Kandola BS, Pye DA, Gallagher JT. Stringer SE, et al. Among authors: gallagher jt. Glycobiology. 2003 Feb;13(2):97-107. doi: 10.1093/glycob/cwg006. Epub 2002 Oct 30. Glycobiology. 2003. PMID: 12626406

5

Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity.

Pye DA, Vives RR, Turnbull JE, Hyde P, Gallagher JT. Pye DA, et al. Among authors: gallagher jt. J Biol Chem. 1998 Sep 4;273(36):22936-42. doi: 10.1074/jbc.273.36.22936. J Biol Chem. 1998. PMID: 9722514 Free article.

6

Monomer complexes of basic fibroblast growth factor and heparan sulfate oligosaccharides are the minimal functional unit for cell activation.

Pye DA, Gallagher JT. Pye DA, et al. Among authors: gallagher jt. J Biol Chem. 1999 May 7;274(19):13456-61. doi: 10.1074/jbc.274.19.13456. J Biol Chem. 1999. PMID: 10224111 Free article.

7

A new model for the domain structure of heparan sulfate based on the novel specificity of K5 lyase.

Murphy KJ, Merry CL, Lyon M, Thompson JE, Roberts IS, Gallagher JT. Murphy KJ, et al. Among authors: gallagher jt. J Biol Chem. 2004 Jun 25;279(26):27239-45. doi: 10.1074/jbc.M401774200. Epub 2004 Mar 26. J Biol Chem. 2004. PMID: 15047699 Free article.

8

Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.

Harmer NJ, Robinson CJ, Adam LE, Ilag LL, Robinson CV, Gallagher JT, Blundell TL. Harmer NJ, et al. Among authors: gallagher jt. Biochem J. 2006 Feb 1;393(Pt 3):741-8. doi: 10.1042/BJ20050985. Biochem J. 2006. PMID: 16223363 Free PMC article.

9

Cooperative heparin-mediated oligomerization of fibroblast growth factor-1 (FGF1) precedes recruitment of FGFR2 to ternary complexes.

Brown A, Robinson CJ, Gallagher JT, Blundell TL. Brown A, et al. Among authors: gallagher jt. Biophys J. 2013 Apr 16;104(8):1720-30. doi: 10.1016/j.bpj.2013.02.051. Biophys J. 2013. PMID: 23601319 Free PMC article.

10

Sequence analysis of heparan sulphate and heparin oligosaccharides.

Vivès RR, Pye DA, Salmivirta M, Hopwood JJ, Lindahl U, Gallagher JT. Vivès RR, et al. Among authors: gallagher jt. Biochem J. 1999 May 1;339 ( Pt 3)(Pt 3):767-73. Biochem J. 1999. PMID: 10215618 Free PMC article.

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