Settanni G - Search Results

1

High temperature unfolding simulations of the TRPZ1 peptide.

Settanni G, Fersht AR. Settanni G, et al. Biophys J. 2008 Jun;94(11):4444-53. doi: 10.1529/biophysj.107.122606. Epub 2008 Feb 15. Biophys J. 2008. PMID: 18281384 Free PMC article.

2

Fluorescence resonance energy transfer analysis of the folding pathway of Engrailed Homeodomain.

Huang F, Settanni G, Fersht AR. Huang F, et al. Among authors: settanni g. Protein Eng Des Sel. 2008 Mar;21(3):131-46. doi: 10.1093/protein/gzm069. Epub 2008 Jan 18. Protein Eng Des Sel. 2008. PMID: 18204045

3

Downhill versus barrier-limited folding of BBL 3. Heterogeneity of the native state of the BBL peripheral subunit binding domain and its implications for folding mechanisms.

Settanni G, Fersht AR. Settanni G, et al. J Mol Biol. 2009 Apr 10;387(4):993-1001. doi: 10.1016/j.jmb.2009.02.014. Epub 2009 Feb 13. J Mol Biol. 2009. PMID: 19217911

4

Combination of Markov state models and kinetic networks for the analysis of molecular dynamics simulations of peptide folding.

Radford IH, Fersht AR, Settanni G. Radford IH, et al. Among authors: settanni g. J Phys Chem B. 2011 Jun 9;115(22):7459-71. doi: 10.1021/jp112158w. Epub 2011 May 9. J Phys Chem B. 2011. PMID: 21553833 Free PMC article.

5

Structure of human MDM4 N-terminal domain bound to a single-domain antibody.

Yu GW, Vaysburd M, Allen MD, Settanni G, Fersht AR. Yu GW, et al. Among authors: settanni g. J Mol Biol. 2009 Feb 6;385(5):1578-89. doi: 10.1016/j.jmb.2008.11.043. Epub 2008 Nov 30. J Mol Biol. 2009. PMID: 19084022

6

Multiple conformations of full-length p53 detected with single-molecule fluorescence resonance energy transfer.

Huang F, Rajagopalan S, Settanni G, Marsh RJ, Armoogum DA, Nicolaou N, Bain AJ, Lerner E, Haas E, Ying L, Fersht AR. Huang F, et al. Among authors: settanni g. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20758-63. doi: 10.1073/pnas.0909644106. Epub 2009 Nov 20. Proc Natl Acad Sci U S A. 2009. PMID: 19933326 Free PMC article.

7

Toward the rational design of p53-stabilizing drugs: probing the surface of the oncogenic Y220C mutant.

Basse N, Kaar JL, Settanni G, Joerger AC, Rutherford TJ, Fersht AR. Basse N, et al. Among authors: settanni g. Chem Biol. 2010 Jan 29;17(1):46-56. doi: 10.1016/j.chembiol.2009.12.011. Chem Biol. 2010. PMID: 20142040

8

Mechanical unfolding of an ankyrin repeat protein.

Serquera D, Lee W, Settanni G, Marszalek PE, Paci E, Itzhaki LS. Serquera D, et al. Among authors: settanni g. Biophys J. 2010 Apr 7;98(7):1294-301. doi: 10.1016/j.bpj.2009.12.4287. Biophys J. 2010. PMID: 20371329 Free PMC article.

9

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm.

Bauer MR, Krämer A, Settanni G, Jones RN, Ni X, Khan Tareque R, Fersht AR, Spencer J, Joerger AC. Bauer MR, et al. Among authors: settanni g. ACS Chem Biol. 2020 Mar 20;15(3):657-668. doi: 10.1021/acschembio.9b00748. Epub 2020 Feb 21. ACS Chem Biol. 2020. PMID: 31990523 Free PMC article.

10

Formation of the folding nucleus of an SH3 domain investigated by loosely coupled molecular dynamics simulations.

Settanni G, Gsponer J, Caflisch A. Settanni G, et al. Biophys J. 2004 Mar;86(3):1691-701. doi: 10.1016/S0006-3495(04)74238-1. Biophys J. 2004. PMID: 14990497 Free PMC article.

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