Kirby B - Search Results

1

Effects of pregnancy on CYP3A and P-glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study.

Hebert MF, Easterling TR, Kirby B, Carr DB, Buchanan ML, Rutherford T, Thummel KE, Fishbein DP, Unadkat JD. Hebert MF, et al. Among authors: kirby b. Clin Pharmacol Ther. 2008 Aug;84(2):248-53. doi: 10.1038/clpt.2008.1. Epub 2008 Feb 20. Clin Pharmacol Ther. 2008. PMID: 18288078 Clinical Trial.

2

Sensitive and specific LC-MS assay for quantification of digoxin in human plasma and urine.

Kirby BJ, Kalhorn T, Hebert M, Easterling T, Unadkat JD. Kirby BJ, et al. Biomed Chromatogr. 2008 Jul;22(7):712-8. doi: 10.1002/bmc.988. Biomed Chromatogr. 2008. PMID: 18317988

3

Grapefruit juice, a glass full of drug interactions?

Kirby BJ, Unadkat JD. Kirby BJ, et al. Clin Pharmacol Ther. 2007 May;81(5):631-3. doi: 10.1038/sj.clpt.6100185. Clin Pharmacol Ther. 2007. PMID: 17438537

4

Simultaneous measurement of in vivo P-glycoprotein and cytochrome P450 3A activities.

Kirby B, Kharasch ED, Thummel KT, Narang VS, Hoffer CJ, Unadkat JD. Kirby B, et al. J Clin Pharmacol. 2006 Nov;46(11):1313-9. doi: 10.1177/0091270006292625. J Clin Pharmacol. 2006. PMID: 17050796 Clinical Trial.

5

Validation of a sensitive LC-MS assay for quantification of glyburide and its metabolite 4-transhydroxy glyburide in plasma and urine: an OPRU Network study.

Naraharisetti SB, Kirby BJ, Hebert MF, Easterling TR, Unadkat JD. Naraharisetti SB, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Dec 1;860(1):34-41. doi: 10.1016/j.jchromb.2007.10.010. Epub 2007 Oct 22. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17980680 Free PMC article.

6

Impact of ignoring extraction ratio when predicting drug-drug interactions, fraction metabolized, and intestinal first-pass contribution.

Kirby BJ, Unadkat JD. Kirby BJ, et al. Drug Metab Dispos. 2010 Nov;38(11):1926-33. doi: 10.1124/dmd.110.034736. Epub 2010 Aug 19. Drug Metab Dispos. 2010. PMID: 20724498 Free PMC article.

7

Complex drug interactions of HIV protease inhibitors 1: inactivation, induction, and inhibition of cytochrome P450 3A by ritonavir or nelfinavir.

Kirby BJ, Collier AC, Kharasch ED, Whittington D, Thummel KE, Unadkat JD. Kirby BJ, et al. Drug Metab Dispos. 2011 Jun;39(6):1070-8. doi: 10.1124/dmd.110.037523. Epub 2011 Mar 15. Drug Metab Dispos. 2011. PMID: 21406602 Free PMC article. Clinical Trial.

8

Complex drug interactions of the HIV protease inhibitors 3: effect of simultaneous or staggered dosing of digoxin and ritonavir, nelfinavir, rifampin, or bupropion.

Kirby BJ, Collier AC, Kharasch ED, Whittington D, Thummel KE, Unadkat JD. Kirby BJ, et al. Drug Metab Dispos. 2012 Mar;40(3):610-6. doi: 10.1124/dmd.111.042705. Epub 2011 Dec 21. Drug Metab Dispos. 2012. PMID: 22190694 Free PMC article.

9

Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir.

Kirby BJ, Collier AC, Kharasch ED, Dixit V, Desai P, Whittington D, Thummel KE, Unadkat JD. Kirby BJ, et al. Drug Metab Dispos. 2011 Dec;39(12):2329-37. doi: 10.1124/dmd.111.038646. Epub 2011 Sep 19. Drug Metab Dispos. 2011. PMID: 21930825 Free PMC article.

10

Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo.

Kaspera R, Kirby BJ, Sahele T, Collier AC, Kharasch ED, Unadkat JD, Totah RA. Kaspera R, et al. Biochem Pharmacol. 2014 Sep 1;91(1):109-18. doi: 10.1016/j.bcp.2014.06.020. Epub 2014 Jun 25. Biochem Pharmacol. 2014. PMID: 24973543 Free PMC article.

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