Oda K - Search Results

1

YM753, a novel histone deacetylase inhibitor, exhibits antitumor activity with selective, sustained accumulation of acetylated histones in tumors in the WiDr xenograft model.

Shindoh N, Mori M, Terada Y, Oda K, Amino N, Kita A, Taniguchi M, Sohda KY, Nagai K, Sowa Y, Masuoka Y, Orita M, Sasamata M, Matsushime H, Furuichi K, Sakai T. Shindoh N, et al. Among authors: oda k. Int J Oncol. 2008 Mar;32(3):545-55. Int J Oncol. 2008. PMID: 18292931

2

Human mass balance, metabolite profile and identification of metabolic enzymes of [¹⁴C]ASP015K, a novel oral janus kinase inhibitor.

Oda K, Cao YJ, Sawamoto T, Nakada N, Fisniku O, Nagasaka Y, Sohda KY. Oda K, et al. Xenobiotica. 2015;45(10):887-902. doi: 10.3109/00498254.2015.1026864. Epub 2015 May 19. Xenobiotica. 2015. PMID: 25986538

3

Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier.

Nagasaka Y, Oda K, Iwatsubo T, Kawamura A, Usui T. Nagasaka Y, et al. Among authors: oda k. Biopharm Drug Dispos. 2012 Sep;33(6):304-15. doi: 10.1002/bdd.1801. Epub 2012 Aug 18. Biopharm Drug Dispos. 2012. PMID: 22847220

4

In vitro/in vivo investigations to examine the gender differences in the pharmacokinetics of novel oral Janus kinase (JAK) inhibitor ASP015K and sulfate metabolite M2 in rats.

Oda K, Nakada N, Nagasaka Y. Oda K, et al. Xenobiotica. 2015;45(6):488-94. doi: 10.3109/00498254.2014.995747. Epub 2014 Dec 24. Xenobiotica. 2015. PMID: 25539455

5

Effect of telaprevir on the metabolism and hepatic uptake of tacrolimus (FK506).

Oda K, Yamano K. Oda K, et al. Biopharm Drug Dispos. 2014 Dec;35(9):501-12. doi: 10.1002/bdd.1913. Epub 2014 Sep 1. Biopharm Drug Dispos. 2014. PMID: 25059890

6

In vitro-in vivo extrapolations to evaluate the effect of concomitant drugs on tacrolimus (FK506) exposure.

Oda K, Yamano K, Otsuka Y. Oda K, et al. Biopharm Drug Dispos. 2015 Jul;36(5):265-74. doi: 10.1002/bdd.1938. Epub 2015 Feb 4. Biopharm Drug Dispos. 2015. PMID: 25600613

7

Simultaneous determination of a novel oral Janus kinase inhibitor ASP015K and its sulfated metabolite in rat plasma using LC-MS/MS.

Oda K, Mera K, Nagasaka Y, Tokoro K. Oda K, et al. Biomed Chromatogr. 2015 Jul;29(7):967-9. doi: 10.1002/bmc.3380. Epub 2014 Nov 7. Biomed Chromatogr. 2015. PMID: 25380383

8

Identification and characterization of metabolites of ASP015K, a novel oral Janus kinase inhibitor, in rats, chimeric mice with humanized liver, and humans.

Nakada N, Oda K. Nakada N, et al. Among authors: oda k. Xenobiotica. 2015;45(9):757-65. doi: 10.3109/00498254.2015.1019594. Epub 2015 Jun 12. Xenobiotica. 2015. PMID: 25869242

9

Impact of genetic deficiencies of P-glycoprotein and breast cancer resistance protein on pharmacokinetics of aripiprazole and dehydroaripiprazole.

Nagasaka Y, Sano T, Oda K, Kawamura A, Usui T. Nagasaka Y, et al. Among authors: oda k. Xenobiotica. 2014 Oct;44(10):926-32. doi: 10.3109/00498254.2014.901585. Epub 2014 Mar 26. Xenobiotica. 2014. PMID: 24666334

10

A drug-drug interaction study to evaluate the impact of peficitinib on OCT1- and MATE1-mediated transport of metformin in healthy volunteers.

Shibata M, Toyoshima J, Kaneko Y, Oda K, Nishimura T. Shibata M, et al. Among authors: oda k. Eur J Clin Pharmacol. 2020 Aug;76(8):1135-1141. doi: 10.1007/s00228-020-02876-2. Epub 2020 May 16. Eur J Clin Pharmacol. 2020. PMID: 32472157 Free PMC article. Clinical Trial.

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