Melillo G - Search Results

1

Separation and SAR study of HIF-1alpha inhibitory tubulosines from Alangium cf. longiflorum.

Klausmeyer P, McCloud TG, Uranchimeg B, Melillo G, Scudiero DA, Cardellina JH 2nd, Shoemaker RH. Klausmeyer P, et al. Among authors: melillo g. Planta Med. 2008 Feb;74(3):258-63. doi: 10.1055/s-2008-1034315. Epub 2008 Feb 26. Planta Med. 2008. PMID: 18302092

2

Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.

Creighton-Gutteridge M, Cardellina JH 2nd, Stephen AG, Rapisarda A, Uranchimeg B, Hite K, Denny WA, Shoemaker RH, Melillo G. Creighton-Gutteridge M, et al. Among authors: melillo g. Clin Cancer Res. 2007 Feb 1;13(3):1010-8. doi: 10.1158/1078-0432.CCR-06-2301. Clin Cancer Res. 2007. PMID: 17289897

3

Identification of a new natural camptothecin analogue in targeted screening for HIF-1alpha inhibitors.

Klausmeyer P, McCloud TG, Melillo G, Scudiero DA, Cardellina JH 2nd, Shoemaker RH. Klausmeyer P, et al. Among authors: melillo g. Planta Med. 2007 Jan;73(1):49-52. doi: 10.1055/s-2006-951767. Planta Med. 2007. PMID: 17315309

4

Cytotoxic and HIF-1alpha inhibitory compounds from Crossosoma bigelovii.

Klausmeyer P, Zhou Q, Scudiero DA, Uranchimeg B, Melillo G, Cardellina JH, Shoemaker RH, Chang CJ, McCloud TG. Klausmeyer P, et al. Among authors: melillo g. J Nat Prod. 2009 May 22;72(5):805-12. doi: 10.1021/np8006342. J Nat Prod. 2009. PMID: 19405508

5

Antiangiogenic agents and HIF-1 inhibitors meet at the crossroads.

Rapisarda A, Shoemaker RH, Melillo G. Rapisarda A, et al. Among authors: melillo g. Cell Cycle. 2009 Dec 15;8(24):4040-3. doi: 10.4161/cc.8.24.10145. Epub 2009 Dec 21. Cell Cycle. 2009. PMID: 19923892

6

Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH, Melillo G. Rapisarda A, et al. Among authors: melillo g. Cancer Res. 2002 Aug 1;62(15):4316-24. Cancer Res. 2002. PMID: 12154035

7

Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications.

Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker RH, Melillo G. Rapisarda A, et al. Among authors: melillo g. Cancer Res. 2004 Feb 15;64(4):1475-82. doi: 10.1158/0008-5472.can-03-3139. Cancer Res. 2004. PMID: 14983893

8

Schedule-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation, angiogenesis, and tumor growth by topotecan in U251-HRE glioblastoma xenografts.

Rapisarda A, Zalek J, Hollingshead M, Braunschweig T, Uranchimeg B, Bonomi CA, Borgel SD, Carter JP, Hewitt SM, Shoemaker RH, Melillo G. Rapisarda A, et al. Among authors: melillo g. Cancer Res. 2004 Oct 1;64(19):6845-8. doi: 10.1158/0008-5472.CAN-04-2116. Cancer Res. 2004. PMID: 15466170

9

Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity.

Kong D, Park EJ, Stephen AG, Calvani M, Cardellina JH, Monks A, Fisher RJ, Shoemaker RH, Melillo G. Kong D, et al. Among authors: melillo g. Cancer Res. 2005 Oct 1;65(19):9047-55. doi: 10.1158/0008-5472.CAN-05-1235. Cancer Res. 2005. PMID: 16204079

10

Hypoxic induction of an HIF-1alpha-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells.

Calvani M, Rapisarda A, Uranchimeg B, Shoemaker RH, Melillo G. Calvani M, et al. Among authors: melillo g. Blood. 2006 Apr 1;107(7):2705-12. doi: 10.1182/blood-2005-09-3541. Epub 2005 Nov 22. Blood. 2006. PMID: 16304044 Free PMC article.

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