Scudiero DA - Search Results

1

Separation and SAR study of HIF-1alpha inhibitory tubulosines from Alangium cf. longiflorum.

Klausmeyer P, McCloud TG, Uranchimeg B, Melillo G, Scudiero DA, Cardellina JH 2nd, Shoemaker RH. Klausmeyer P, et al. Among authors: scudiero da. Planta Med. 2008 Feb;74(3):258-63. doi: 10.1055/s-2008-1034315. Epub 2008 Feb 26. Planta Med. 2008. PMID: 18302092

2

Identification of a new natural camptothecin analogue in targeted screening for HIF-1alpha inhibitors.

Klausmeyer P, McCloud TG, Melillo G, Scudiero DA, Cardellina JH 2nd, Shoemaker RH. Klausmeyer P, et al. Among authors: scudiero da. Planta Med. 2007 Jan;73(1):49-52. doi: 10.1055/s-2006-951767. Planta Med. 2007. PMID: 17315309

3

Cytotoxic and HIF-1alpha inhibitory compounds from Crossosoma bigelovii.

Klausmeyer P, Zhou Q, Scudiero DA, Uranchimeg B, Melillo G, Cardellina JH, Shoemaker RH, Chang CJ, McCloud TG. Klausmeyer P, et al. Among authors: scudiero da. J Nat Prod. 2009 May 22;72(5):805-12. doi: 10.1021/np8006342. J Nat Prod. 2009. PMID: 19405508

4

Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH, Melillo G. Rapisarda A, et al. Among authors: scudiero da. Cancer Res. 2002 Aug 1;62(15):4316-24. Cancer Res. 2002. PMID: 12154035

5

Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa.

Meragelman TL, Scudiero DA, Davis RE, Staudt LM, McCloud TG, Cardellina JH 2nd, Shoemaker RH. Meragelman TL, et al. Among authors: scudiero da. J Nat Prod. 2009 Mar 27;72(3):336-9. doi: 10.1021/np800350x. J Nat Prod. 2009. PMID: 19093800

6

Discovery and preliminary SAR of bisbenzylisoquinoline alkaloids as inducers of C/EBPα.

Klausmeyer P, McCloud TG, Scudiero DA, Currens MJ, Cardellina Ii JH, Shoemaker RH. Klausmeyer P, et al. Among authors: scudiero da. Bioorg Med Chem. 2012 Aug 1;20(15):4646-52. doi: 10.1016/j.bmc.2012.06.017. Epub 2012 Jun 16. Bioorg Med Chem. 2012. PMID: 22766217 Free PMC article.

7

Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore.

Nguyen TL, Gussio R, Smith JA, Lannigan DA, Hecht SM, Scudiero DA, Shoemaker RH, Zaharevitz DW. Nguyen TL, et al. Among authors: scudiero da. Bioorg Med Chem. 2006 Sep 1;14(17):6097-105. doi: 10.1016/j.bmc.2006.05.001. Epub 2006 May 24. Bioorg Med Chem. 2006. PMID: 16723234

8

Identification of a Bis-guanylhydrazone [4,4'-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Chk2 kinase.

Jobson AG, Cardellina JH 2nd, Scudiero D, Kondapaka S, Zhang H, Kim H, Shoemaker R, Pommier Y. Jobson AG, et al. Mol Pharmacol. 2007 Oct;72(4):876-84. doi: 10.1124/mol.107.035832. Epub 2007 Jul 6. Mol Pharmacol. 2007. PMID: 17616632

9

Application of high-throughput, molecular-targeted screening to anticancer drug discovery.

Shoemaker RH, Scudiero DA, Melillo G, Currens MJ, Monks AP, Rabow AA, Covell DG, Sausville EA. Shoemaker RH, et al. Among authors: scudiero da. Curr Top Med Chem. 2002 Mar;2(3):229-46. doi: 10.2174/1568026023394317. Curr Top Med Chem. 2002. PMID: 11944818 Review.

10

12 Arylstibonic acids that inhibit the DNA binding of five B-ZIP dimers.

Rishi V, Oh WJ, Heyerdahl SL, Zhao J, Scudiero D, Shoemaker RH, Vinson C. Rishi V, et al. J Struct Biol. 2010 May;170(2):216-25. doi: 10.1016/j.jsb.2010.02.013. Epub 2010 Feb 20. J Struct Biol. 2010. PMID: 20176111 Free PMC article.

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