Klutz AM - Search Results

1

Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists.

Ivanov AA, Wang B, Klutz AM, Chen VL, Gao ZG, Jacobson KA. Ivanov AA, et al. Among authors: klutz am. J Med Chem. 2008 Apr 10;51(7):2088-99. doi: 10.1021/jm701442d. Epub 2008 Mar 6. J Med Chem. 2008. PMID: 18321038 Free PMC article.

2

"Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists.

Perreira M, Jiang JK, Klutz AM, Gao ZG, Shainberg A, Lu C, Thomas CJ, Jacobson KA. Perreira M, et al. Among authors: klutz am. J Med Chem. 2005 Jul 28;48(15):4910-8. doi: 10.1021/jm050221l. J Med Chem. 2005. PMID: 16033270 Free PMC article.

3

Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety.

Gao ZG, Joshi BV, Klutz AM, Kim SK, Lee HW, Kim HO, Jeong LS, Jacobson KA. Gao ZG, et al. Among authors: klutz am. Bioorg Med Chem Lett. 2006 Feb;16(3):596-601. doi: 10.1016/j.bmcl.2005.10.054. Epub 2005 Nov 10. Bioorg Med Chem Lett. 2006. PMID: 16289820 Free PMC article.

4

Structure-activity relationships of truncated D- and l-4'-thioadenosine derivatives as species-independent A3 adenosine receptor antagonists.

Jeong LS, Pal S, Choe SA, Choi WJ, Jacobson KA, Gao ZG, Klutz AM, Hou X, Kim HO, Lee HW, Lee SK, Tosh DK, Moon HR. Jeong LS, et al. Among authors: klutz am. J Med Chem. 2008 Oct 23;51(20):6609-13. doi: 10.1021/jm8008647. Epub 2008 Sep 24. J Med Chem. 2008. PMID: 18811138 Free PMC article.

5

Functionalized congeners of A3 adenosine receptor-selective nucleosides containing a bicyclo[3.1.0]hexane ring system.

Tosh DK, Chinn M, Ivanov AA, Klutz AM, Gao ZG, Jacobson KA. Tosh DK, et al. Among authors: klutz am. J Med Chem. 2009 Dec 10;52(23):7580-92. doi: 10.1021/jm900426g. J Med Chem. 2009. PMID: 19499950 Free PMC article.

6

Medicinal chemistry of the A3 adenosine receptor: agonists, antagonists, and receptor engineering.

Jacobson KA, Klutz AM, Tosh DK, Ivanov AA, Preti D, Baraldi PG. Jacobson KA, et al. Among authors: klutz am. Handb Exp Pharmacol. 2009;(193):123-59. doi: 10.1007/978-3-540-89615-9_5. Handb Exp Pharmacol. 2009. PMID: 19639281 Free PMC article. Review.

7

Toward multivalent signaling across G protein-coupled receptors from poly(amidoamine) dendrimers.

Kim Y, Hechler B, Klutz AM, Gachet C, Jacobson KA. Kim Y, et al. Among authors: klutz am. Bioconjug Chem. 2008 Feb;19(2):406-11. doi: 10.1021/bc700327u. Epub 2008 Jan 5. Bioconjug Chem. 2008. PMID: 18176997 Free PMC article.

8

Application of the functionalized congener approach to dendrimer-based signaling agents acting through A(2A) adenosine receptors.

Kim Y, Klutz AM, Hechler B, Gao ZG, Gachet C, Jacobson KA. Kim Y, et al. Among authors: klutz am. Purinergic Signal. 2009 Mar;5(1):39-50. doi: 10.1007/s11302-008-9113-3. Epub 2008 Jul 4. Purinergic Signal. 2009. PMID: 18600474 Free PMC article.

9

Systematic investigation of polyamidoamine dendrimers surface-modified with poly(ethylene glycol) for drug delivery applications: synthesis, characterization, and evaluation of cytotoxicity.

Kim Y, Klutz AM, Jacobson KA. Kim Y, et al. Among authors: klutz am. Bioconjug Chem. 2008 Aug;19(8):1660-72. doi: 10.1021/bc700483s. Epub 2008 Jul 9. Bioconjug Chem. 2008. PMID: 18610944 Free PMC article.

10

Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.

Klutz AM, Gao ZG, Lloyd J, Shainberg A, Jacobson KA. Klutz AM, et al. J Nanobiotechnology. 2008 Oct 23;6:12. doi: 10.1186/1477-3155-6-12. J Nanobiotechnology. 2008. PMID: 18947419 Free PMC article.

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