Bassell GJ - Search Results

1

Reducing glutamate signaling pays off in fragile X.

Bassell GJ, Gross C. Bassell GJ, et al. Nat Med. 2008 Mar;14(3):249-50. doi: 10.1038/nm0308-249. Nat Med. 2008. PMID: 18323845 No abstract available.

2

Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond.

Gross C, Berry-Kravis EM, Bassell GJ. Gross C, et al. Among authors: bassell gj. Neuropsychopharmacology. 2012 Jan;37(1):178-95. doi: 10.1038/npp.2011.137. Epub 2011 Jul 27. Neuropsychopharmacology. 2012. PMID: 21796106 Free PMC article. Review.

3

Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.

Gross C, Chang CW, Kelly SM, Bhattacharya A, McBride SM, Danielson SW, Jiang MQ, Chan CB, Ye K, Gibson JR, Klann E, Jongens TA, Moberg KH, Huber KM, Bassell GJ. Gross C, et al. Among authors: bassell gj. Cell Rep. 2015 May 5;11(5):727-36. doi: 10.1016/j.celrep.2015.03.060. Epub 2015 Apr 23. Cell Rep. 2015. PMID: 25921541 Free PMC article.

4

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome.

Muddashetty RS, Kelić S, Gross C, Xu M, Bassell GJ. Muddashetty RS, et al. Among authors: bassell gj. J Neurosci. 2007 May 16;27(20):5338-48. doi: 10.1523/JNEUROSCI.0937-07.2007. J Neurosci. 2007. PMID: 17507556 Free PMC article.

5

Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.

Gross C, Yao X, Pong DL, Jeromin A, Bassell GJ. Gross C, et al. Among authors: bassell gj. J Neurosci. 2011 Apr 13;31(15):5693-8. doi: 10.1523/JNEUROSCI.6661-10.2011. J Neurosci. 2011. PMID: 21490210 Free PMC article.

6

Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling.

Muddashetty RS, Nalavadi VC, Gross C, Yao X, Xing L, Laur O, Warren ST, Bassell GJ. Muddashetty RS, et al. Among authors: bassell gj. Mol Cell. 2011 Jun 10;42(5):673-88. doi: 10.1016/j.molcel.2011.05.006. Mol Cell. 2011. PMID: 21658607 Free PMC article.

7

Selective role of the catalytic PI3K subunit p110β in impaired higher order cognition in fragile X syndrome.

Gross C, Raj N, Molinaro G, Allen AG, Whyte AJ, Gibson JR, Huber KM, Gourley SL, Bassell GJ. Gross C, et al. Among authors: bassell gj. Cell Rep. 2015 May 5;11(5):681-8. doi: 10.1016/j.celrep.2015.03.065. Epub 2015 Apr 23. Cell Rep. 2015. PMID: 25921527 Free PMC article.

8

Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.

Gross C, Nakamoto M, Yao X, Chan CB, Yim SY, Ye K, Warren ST, Bassell GJ. Gross C, et al. Among authors: bassell gj. J Neurosci. 2010 Aug 11;30(32):10624-38. doi: 10.1523/JNEUROSCI.0402-10.2010. J Neurosci. 2010. PMID: 20702695 Free PMC article.

9

Excess protein synthesis in FXS patient lymphoblastoid cells can be rescued with a p110β-selective inhibitor.

Gross C, Bassell GJ. Gross C, et al. Among authors: bassell gj. Mol Med. 2012 May 9;18(1):336-45. doi: 10.2119/molmed.2011.00363. Mol Med. 2012. PMID: 22207187 Free PMC article.

10

Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation.

Nalavadi VC, Muddashetty RS, Gross C, Bassell GJ. Nalavadi VC, et al. Among authors: bassell gj. J Neurosci. 2012 Feb 22;32(8):2582-7. doi: 10.1523/JNEUROSCI.5057-11.2012. J Neurosci. 2012. PMID: 22357842 Free PMC article.

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