Xia W - Search Results

1

The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions.

Zhang B, Dong Y, Zhang G, Moir RD, Xia W, Yue Y, Tian M, Culley DJ, Crosby G, Tanzi RE, Xie Z. Zhang B, et al. Among authors: xia w. J Biol Chem. 2008 May 2;283(18):11866-75. doi: 10.1074/jbc.M800199200. Epub 2008 Mar 6. J Biol Chem. 2008. PMID: 18326038 Free PMC article.

2

RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation.

Xie Z, Dong Y, Maeda U, Xia W, Tanzi RE. Xie Z, et al. Among authors: xia w. J Biol Chem. 2007 Feb 16;282(7):4318-4325. doi: 10.1074/jbc.M609293200. Epub 2006 Dec 14. J Biol Chem. 2007. PMID: 17170108 Free article.

3

The inhalation anesthetic isoflurane induces a vicious cycle of apoptosis and amyloid beta-protein accumulation.

Xie Z, Dong Y, Maeda U, Moir RD, Xia W, Culley DJ, Crosby G, Tanzi RE. Xie Z, et al. Among authors: xia w. J Neurosci. 2007 Feb 7;27(6):1247-54. doi: 10.1523/JNEUROSCI.5320-06.2007. J Neurosci. 2007. PMID: 17287498 Free PMC article.

4

HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation.

Huttunen HJ, Guénette SY, Peach C, Greco C, Xia W, Kim DY, Barren C, Tanzi RE, Kovacs DM. Huttunen HJ, et al. Among authors: xia w. J Biol Chem. 2007 Sep 21;282(38):28285-95. doi: 10.1074/jbc.M702951200. Epub 2007 Aug 6. J Biol Chem. 2007. PMID: 17684015 Free article.

5

The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels.

Dong Y, Zhang G, Zhang B, Moir RD, Xia W, Marcantonio ER, Culley DJ, Crosby G, Tanzi RE, Xie Z. Dong Y, et al. Among authors: xia w. Arch Neurol. 2009 May;66(5):620-31. doi: 10.1001/archneurol.2009.48. Arch Neurol. 2009. PMID: 19433662 Free PMC article.

6

RNAi-mediated knock-down of Dab and Numb attenuate Aβ levels via γ-secretase mediated APP processing.

Xie Z, Dong Y, Maeda U, Xia W, Tanzi RE. Xie Z, et al. Among authors: xia w. Transl Neurodegener. 2012 Mar 22;1(1):8. doi: 10.1186/2047-9158-1-8. Transl Neurodegener. 2012. PMID: 23211096 Free PMC article.

7

Chronic treatment with anesthetic propofol improves cognitive function and attenuates caspase activation in both aged and Alzheimer's disease transgenic mice.

Shao H, Zhang Y, Dong Y, Yu B, Xia W, Xie Z. Shao H, et al. Among authors: xia w. J Alzheimers Dis. 2014;41(2):499-513. doi: 10.3233/JAD-132792. J Alzheimers Dis. 2014. PMID: 24643139 Free PMC article.

8

Chronic treatment with anesthetic propofol attenuates β-amyloid protein levels in brain tissues of aged mice.

Zhang Y, Shao H, Dong Y, Swain CA, Yu B, Xia W, Xie Z. Zhang Y, et al. Among authors: xia w. Transl Neurodegener. 2014 Apr 11;3(1):8. doi: 10.1186/2047-9158-3-8. Transl Neurodegener. 2014. PMID: 24725331 Free PMC article.

9

The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation.

Kimberly WT, Xia W, Rahmati T, Wolfe MS, Selkoe DJ. Kimberly WT, et al. Among authors: xia w. J Biol Chem. 2000 Feb 4;275(5):3173-8. doi: 10.1074/jbc.275.5.3173. J Biol Chem. 2000. PMID: 10652302 Free article.

10

Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer's disease.

Kwak SS, Washicosky KJ, Brand E, von Maydell D, Aronson J, Kim S, Capen DE, Cetinbas M, Sadreyev R, Ning S, Bylykbashi E, Xia W, Wagner SL, Choi SH, Tanzi RE, Kim DY. Kwak SS, et al. Among authors: xia w. Nat Commun. 2020 Mar 13;11(1):1377. doi: 10.1038/s41467-020-15120-3. Nat Commun. 2020. PMID: 32170138 Free PMC article.

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