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Simultaneously targeting CD45 significantly increases cytotoxicity of the anti-CD33 immunoconjugate, gemtuzumab ozogamicin, against acute myeloid leukemia (AML) cells and improves survival of mice bearing human AML xenografts.
Walter RB, Boyle KM, Appelbaum FR, Bernstein ID, Pagel JM. Walter RB, et al. Among authors: pagel jm. Blood. 2008 May 1;111(9):4813-6. doi: 10.1182/blood-2008-01-133785. Epub 2008 Mar 7. Blood. 2008. PMID: 18326813 Free PMC article.
Allogeneic hematopoietic cell transplantation for chronic myelomonocytic leukemia.
Kerbauy DM, Chyou F, Gooley T, Sorror ML, Scott B, Pagel JM, Myerson D, Appelbaum FR, Storb R, Deeg HJ. Kerbauy DM, et al. Among authors: pagel jm. Biol Blood Marrow Transplant. 2005 Sep;11(9):713-20. doi: 10.1016/j.bbmt.2005.05.008. Biol Blood Marrow Transplant. 2005. PMID: 16125642 Free article.
131I-anti-CD45 antibody plus busulfan and cyclophosphamide before allogeneic hematopoietic cell transplantation for treatment of acute myeloid leukemia in first remission.
Pagel JM, Appelbaum FR, Eary JF, Rajendran J, Fisher DR, Gooley T, Ruffner K, Nemecek E, Sickle E, Durack L, Carreras J, Horowitz MM, Press OW, Gopal AK, Martin PJ, Bernstein ID, Matthews DC. Pagel JM, et al. Blood. 2006 Mar 1;107(5):2184-91. doi: 10.1182/blood-2005-06-2317. Epub 2005 Oct 27. Blood. 2006. PMID: 16254140 Free PMC article. Clinical Trial.
206 results