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Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Gupta A, Mugundu GM, Desai PB, Thummel KE, Unadkat JD. Gupta A, et al. Drug Metab Dispos. 2008 Jun;36(6):1172-80. doi: 10.1124/dmd.107.018689. Epub 2008 Mar 10. Drug Metab Dispos. 2008. PMID: 18332086
Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex.
Prasad B, Evers R, Gupta A, Hop CE, Salphati L, Shukla S, Ambudkar SV, Unadkat JD. Prasad B, et al. Among authors: gupta a. Drug Metab Dispos. 2014 Jan;42(1):78-88. doi: 10.1124/dmd.113.053819. Epub 2013 Oct 11. Drug Metab Dispos. 2014. PMID: 24122874 Free PMC article.
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