Herpes simplex virus thymidine kinase mutations associated with resistance to acyclovir: a site-directed mutagenesis study.
Frobert E, Ooka T, Cortay JC, Lina B, Thouvenot D, Morfin F.
Frobert E, et al. Among authors: ooka t.
Antimicrob Agents Chemother. 2005 Mar;49(3):1055-9. doi: 10.1128/AAC.49.3.1055-1059.2005.
Antimicrob Agents Chemother. 2005.
PMID: 15728902
Free PMC article.
To assess the role of the mutations located at codons 51, 77, 83, and 175, previously detected in HSV-1 clinical isolates (F. Morfin, G. Souillet, K. Bilger, T. Ooka, M. Aymard, and D. Thouvenot, J. Infect. Dis. 182:290-293, 2000), in the acquisition of resistance t …
To assess the role of the mutations located at codons 51, 77, 83, and 175, previously detected in HSV-1 clinical isolates (F. Morfin, G. Sou …