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The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease.
Henderson KN, Reid HH, Borg NA, Broughton SE, Huyton T, Anderson RP, McCluskey J, Rossjohn J. Henderson KN, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt 12):1021-5. doi: 10.1107/S1744309107051408. Epub 2007 Nov 21. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 18084083 Free PMC article.
Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.
Broughton SE, Petersen J, Theodossis A, Scally SW, Loh KL, Thompson A, van Bergen J, Kooy-Winkelaar Y, Henderson KN, Beddoe T, Tye-Din JA, Mannering SI, Purcell AW, McCluskey J, Anderson RP, Koning F, Reid HH, Rossjohn J. Broughton SE, et al. Among authors: henderson kn. Immunity. 2012 Oct 19;37(4):611-21. doi: 10.1016/j.immuni.2012.07.013. Epub 2012 Oct 11. Immunity. 2012. PMID: 23063329 Free article.
X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
McGowan S, Buckle AM, Irving JA, Ong PC, Bashtannyk-Puhalovich TA, Kan WT, Henderson KN, Bulynko YA, Popova EY, Smith AI, Bottomley SP, Rossjohn J, Grigoryev SA, Pike RN, Whisstock JC. McGowan S, et al. Among authors: henderson kn. EMBO J. 2006 Jul 12;25(13):3144-55. doi: 10.1038/sj.emboj.7601201. Epub 2006 Jun 29. EMBO J. 2006. PMID: 16810322 Free PMC article.
Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.
Tye-Din JA, Stewart JA, Dromey JA, Beissbarth T, van Heel DA, Tatham A, Henderson K, Mannering SI, Gianfrani C, Jewell DP, Hill AV, McCluskey J, Rossjohn J, Anderson RP. Tye-Din JA, et al. Sci Transl Med. 2010 Jul 21;2(41):41ra51. doi: 10.1126/scitranslmed.3001012. Sci Transl Med. 2010. PMID: 20650871