Booth RG - Search Results

1

Molecular determinants of ligand-directed signaling for the histamine H1 receptor.

Booth RG, Fang L, Wilczynski A, Sivendren S, Sun Z, Travers S, Bruysters M, Sansuk K, Leurs R. Booth RG, et al. Inflamm Res. 2008;57 Suppl 1(0 1):S43-4. doi: 10.1007/s00011-007-0621-3. Inflamm Res. 2008. PMID: 18345497 Free PMC article. No abstract available.

2

Novel ligands stabilize stereo-selective conformations of the histamine H1 receptor to activate catecholamine synthesis.

Booth RG, Moniri NH. Booth RG, et al. Inflamm Res. 2007 Apr;56 Suppl 1:S43-4. doi: 10.1007/s00011-006-0521-y. Inflamm Res. 2007. PMID: 17806174 No abstract available.

3

Molecular determinants of ligand binding at the human histamine H₁ receptor: Site-directed mutagenesis results analyzed with ligand docking and molecular dynamics studies at H₁ homology and crystal structure models.

Cordova-Sintjago TC, Fang L, Bruysters M, Leurs R, Booth RG. Cordova-Sintjago TC, et al. Among authors: booth rg. J Chem Pharm Res. 2012 Jun;4(6):2937-2951. J Chem Pharm Res. 2012. PMID: 25013351 Free PMC article.

4

Novel 4-substituted-N,N-dimethyltetrahydronaphthalen-2-amines: synthesis, affinity, and in silico docking studies at serotonin 5-HT2-type and histamine H1 G protein-coupled receptors.

Sakhuja R, Kondabolu K, Córdova-Sintjago T, Travers S, Vincek AS, Kim MS, Abboud KA, Fang L, Sun Z, Canal CE, Booth RG. Sakhuja R, et al. Among authors: booth rg. Bioorg Med Chem. 2015 Apr 1;23(7):1588-600. doi: 10.1016/j.bmc.2015.01.060. Epub 2015 Feb 7. Bioorg Med Chem. 2015. PMID: 25703249 Free PMC article.

5

(1R, 3S)-(-)-trans-PAT: a novel full-efficacy serotonin 5-HT2C receptor agonist with 5-HT2A and 5-HT2B receptor inverse agonist/antagonist activity.

Booth RG, Fang L, Huang Y, Wilczynski A, Sivendran S. Booth RG, et al. Eur J Pharmacol. 2009 Aug 1;615(1-3):1-9. doi: 10.1016/j.ejphar.2009.04.035. Epub 2009 May 3. Eur J Pharmacol. 2009. PMID: 19397907 Free PMC article.

6

GPCR proteomics: mass spectrometric and functional analysis of histamine H1 receptor after baculovirus-driven and in vitro cell free expression.

Sansuk K, Balog CI, van der Does AM, Booth R, de Grip WJ, Deelder AM, Bakker RA, Leurs R, Hensbergen PJ. Sansuk K, et al. J Proteome Res. 2008 Feb;7(2):621-9. doi: 10.1021/pr7005654. J Proteome Res. 2008. PMID: 18177001

7

Ligand-directed multifunctional signaling of histamine H1 receptors.

Booth RG, Moniri NH. Booth RG, et al. Inflamm Res. 2005 Apr;54 Suppl 1:S44-5. doi: 10.1007/s00011-004-0420-z. Inflamm Res. 2005. PMID: 15928829 No abstract available.

8

A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors.

Booth RG, Moniri NH, Bakker RA, Choksi NY, Nix WB, Timmerman H, Leurs R. Booth RG, et al. J Pharmacol Exp Ther. 2002 Jul;302(1):328-36. doi: 10.1124/jpet.302.1.328. J Pharmacol Exp Ther. 2002. PMID: 12065734

9

Domain swapping in the human histamine H1 receptor.

Bakker RA, Dees G, Carrillo JJ, Booth RG, López-Gimenez JF, Milligan G, Strange PG, Leurs R. Bakker RA, et al. Among authors: booth rg. J Pharmacol Exp Ther. 2004 Oct;311(1):131-8. doi: 10.1124/jpet.104.067041. Epub 2004 May 24. J Pharmacol Exp Ther. 2004. PMID: 15159444

10

Drug discovery targeting human 5-HT(2C) receptors: residues S3.36 and Y7.43 impact ligand-binding pocket structure via hydrogen bond formation.

Canal CE, Cordova-Sintjago TC, Villa NY, Fang LJ, Booth RG. Canal CE, et al. Among authors: booth rg. Eur J Pharmacol. 2011 Dec 30;673(1-3):1-12. doi: 10.1016/j.ejphar.2011.10.006. Epub 2011 Oct 12. Eur J Pharmacol. 2011. PMID: 22020288 Free PMC article.

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