Leurs R - Search Results

1

Molecular determinants of ligand-directed signaling for the histamine H1 receptor.

Booth RG, Fang L, Wilczynski A, Sivendren S, Sun Z, Travers S, Bruysters M, Sansuk K, Leurs R. Booth RG, et al. Among authors: leurs r. Inflamm Res. 2008;57 Suppl 1(0 1):S43-4. doi: 10.1007/s00011-007-0621-3. Inflamm Res. 2008. PMID: 18345497 Free PMC article. No abstract available.

2

A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors.

Booth RG, Moniri NH, Bakker RA, Choksi NY, Nix WB, Timmerman H, Leurs R. Booth RG, et al. Among authors: leurs r. J Pharmacol Exp Ther. 2002 Jul;302(1):328-36. doi: 10.1124/jpet.302.1.328. J Pharmacol Exp Ther. 2002. PMID: 12065734

3

Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens.

Bruysters M, Pertz HH, Teunissen A, Bakker RA, Gillard M, Chatelain P, Schunack W, Timmerman H, Leurs R. Bruysters M, et al. Among authors: leurs r. Eur J Pharmacol. 2004 Mar 8;487(1-3):55-63. doi: 10.1016/j.ejphar.2004.01.028. Eur J Pharmacol. 2004. PMID: 15033376

4

Domain swapping in the human histamine H1 receptor.

Bakker RA, Dees G, Carrillo JJ, Booth RG, López-Gimenez JF, Milligan G, Strange PG, Leurs R. Bakker RA, et al. Among authors: leurs r. J Pharmacol Exp Ther. 2004 Oct;311(1):131-8. doi: 10.1124/jpet.104.067041. Epub 2004 May 24. J Pharmacol Exp Ther. 2004. PMID: 15159444

5

Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor.

Ratnala VR, Swarts HG, VanOostrum J, Leurs R, DeGroot HJ, Bakker RA, DeGrip WJ. Ratnala VR, et al. Among authors: leurs r. Eur J Biochem. 2004 Jul;271(13):2636-46. doi: 10.1111/j.1432-1033.2004.04192.x. Eur J Biochem. 2004. PMID: 15206929 Free article.

6

Pharmacological differences between human and guinea pig histamine H1 receptors: Asn84 (2.61) as key residue within an additional binding pocket in the H1 receptor.

Bruysters M, Jongejan A, Gillard M, van de Manakker F, Bakker RA, Chatelain P, Leurs R. Bruysters M, et al. Among authors: leurs r. Mol Pharmacol. 2005 Apr;67(4):1045-52. doi: 10.1124/mol.104.008847. Epub 2004 Dec 30. Mol Pharmacol. 2005. PMID: 15626750

7

A G(q/11)-coupled mutant histamine H(1) receptor F435A activated solely by synthetic ligands (RASSL).

Bruysters M, Jongejan A, Akdemir A, Bakker RA, Leurs R. Bruysters M, et al. Among authors: leurs r. J Biol Chem. 2005 Oct 14;280(41):34741-6. doi: 10.1074/jbc.M504165200. Epub 2005 Jul 18. J Biol Chem. 2005. PMID: 16027157 Free article.

8

Linking agonist binding to histamine H1 receptor activation.

Jongejan A, Bruysters M, Ballesteros JA, Haaksma E, Bakker RA, Pardo L, Leurs R. Jongejan A, et al. Among authors: leurs r. Nat Chem Biol. 2005 Jul;1(2):98-103. doi: 10.1038/nchembio714. Epub 2005 Jun 19. Nat Chem Biol. 2005. PMID: 16408006

9

Oligomerization of recombinant and endogenously expressed human histamine H(4) receptors.

van Rijn RM, Chazot PL, Shenton FC, Sansuk K, Bakker RA, Leurs R. van Rijn RM, et al. Among authors: leurs r. Mol Pharmacol. 2006 Aug;70(2):604-15. doi: 10.1124/mol.105.020818. Epub 2006 Apr 27. Mol Pharmacol. 2006. PMID: 16645125

10

Molecular aspects of the histamine H3 receptor.

Bongers G, Bakker RA, Leurs R. Bongers G, et al. Among authors: leurs r. Biochem Pharmacol. 2007 Apr 15;73(8):1195-204. doi: 10.1016/j.bcp.2007.01.008. Epub 2007 Jan 7. Biochem Pharmacol. 2007. PMID: 17276412

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