Younis HS - Search Results

1

An assessment of the ocular safety of inactive excipients following sub-tenon injection in rabbits.

Younis HS, Shawer M, Palacio K, Gukasyan HJ, Stevens GJ, Evering W. Younis HS, et al. J Ocul Pharmacol Ther. 2008 Apr;24(2):206-16. doi: 10.1089/jop.2007.0099. J Ocul Pharmacol Ther. 2008. PMID: 18345993

2

Safety Assessment of Formulation Vehicles Following Intravitreal Administration in Rabbits.

Aguirre SA, Gukasyan HJ, Younis HS, Huang W. Aguirre SA, et al. Among authors: younis hs. Pharm Res. 2018 Jul 9;35(9):173. doi: 10.1007/s11095-018-2450-1. Pharm Res. 2018. PMID: 29987391

3

L-Carnosine: multifunctional dipeptide buffer for sustained-duration topical ophthalmic formulations.

Singh SR, Carreiro ST, Chu J, Prasanna G, Niesman MR, Collette Iii WW, Younis HS, Sartnurak S, Gukasyan HJ. Singh SR, et al. Among authors: younis hs. J Pharm Pharmacol. 2009 Jun;61(6):733-42. doi: 10.1211/jpp/61.06.0005. J Pharm Pharmacol. 2009. PMID: 19505363

4

PD0325901, a mitogen-activated protein kinase kinase inhibitor, produces ocular toxicity in a rabbit animal model of retinal vein occlusion.

Huang W, Yang AH, Matsumoto D, Collette W, Marroquin L, Ko M, Aguirre S, Younis HS. Huang W, et al. Among authors: younis hs. J Ocul Pharmacol Ther. 2009 Dec;25(6):519-30. doi: 10.1089/jop.2009.0060. J Ocul Pharmacol Ther. 2009. PMID: 19929595

5

Effect of PF-04217329 a prodrug of a selective prostaglandin EP(2) agonist on intraocular pressure in preclinical models of glaucoma.

Prasanna G, Carreiro S, Anderson S, Gukasyan H, Sartnurak S, Younis H, Gale D, Xiang C, Wells P, Dinh D, Almaden C, Fortner J, Toris C, Niesman M, Lafontaine J, Krauss A. Prasanna G, et al. Exp Eye Res. 2011 Sep;93(3):256-64. doi: 10.1016/j.exer.2011.02.015. Epub 2011 Mar 3. Exp Eye Res. 2011. PMID: 21376717

6

Antisense inhibition of S6 kinase 1 produces improved glucose tolerance and is well tolerated for 4 weeks of treatment in rats.

Younis HS, Hirakawa B, Scott W, Tran P, Bhat G, Affolter T, Chapman J, Heyen J, Chakravarty K, Alton G. Younis HS, et al. Pharmacology. 2011;87(1-2):11-23. doi: 10.1159/000322526. Epub 2010 Dec 20. Pharmacology. 2011. PMID: 21178385

7

Inhibiting matrix metalloproteinases with prinomastat produces abnormalities in fetal growth and development in rats.

Younis HS, Jessen BA, Wu EY, Stevens GJ. Younis HS, et al. Birth Defects Res B Dev Reprod Toxicol. 2006 Apr;77(2):95-103. doi: 10.1002/bdrb.20073. Birth Defects Res B Dev Reprod Toxicol. 2006. PMID: 16607633

8

Antisense inhibition of 11betahydroxysteroid dehydrogenase type 1 improves diabetes in a novel cortisone-induced diabetic KK mouse model.

Bhat BG, Younis H, Herrera J, Palacio K, Pascual B, Hur G, Jessen B, Ogilvie KM, Rejto PA. Bhat BG, et al. Biochem Biophys Res Commun. 2008 Jan 25;365(4):740-5. doi: 10.1016/j.bbrc.2007.11.032. Epub 2007 Nov 20. Biochem Biophys Res Commun. 2008. PMID: 18029262

9

Identification and characterization of modified antisense oligonucleotides targeting DMPK in mice and nonhuman primates for the treatment of myotonic dystrophy type 1.

Pandey SK, Wheeler TM, Justice SL, Kim A, Younis HS, Gattis D, Jauvin D, Puymirat J, Swayze EE, Freier SM, Bennett CF, Thornton CA, MacLeod AR. Pandey SK, et al. Among authors: younis hs. J Pharmacol Exp Ther. 2015 Nov;355(2):329-40. doi: 10.1124/jpet.115.226969. Epub 2015 Sep 1. J Pharmacol Exp Ther. 2015. PMID: 26330536 Free PMC article.

10

Mechanistic understanding for the greater sensitivity of monkeys to antisense oligonucleotide-mediated complement activation compared with humans.

Shen L, Frazer-Abel A, Reynolds PR, Giclas PC, Chappell A, Pangburn MK, Younis H, Henry SP. Shen L, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):709-17. doi: 10.1124/jpet.114.219378. Epub 2014 Oct 9. J Pharmacol Exp Ther. 2014. PMID: 25301170 Clinical Trial.

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