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Rab18 is reduced in pituitary tumors causing acromegaly and its overexpression reverts growth hormone hypersecretion.
Vazquez-Martinez R, Martinez-Fuentes AJ, Pulido MR, Jimenez-Reina L, Quintero A, Leal-Cerro A, Soto A, Webb SM, Sucunza N, Bartumeus F, Benito-Lopez P, Galvez-Moreno MA, Castaño JP, Malagon MM. Vazquez-Martinez R, et al. J Clin Endocrinol Metab. 2008 Jun;93(6):2269-76. doi: 10.1210/jc.2007-1893. Epub 2008 Mar 18. J Clin Endocrinol Metab. 2008. PMID: 18349058
Ghrelin is produced by and directly activates corticotrope cells from adrenocorticotropin-secreting adenomas.
Martínez-Fuentes AJ, Moreno-Fernández J, Vázquez-Martínez R, Durán-Prado M, de la Riva A, Tena-Sempere M, Diéguez C, Jiménez-Reina L, Webb SM, Pumar A, Leal-Cerro A, Benito-López P, Malagón MM, Castaño JP. Martínez-Fuentes AJ, et al. J Clin Endocrinol Metab. 2006 Jun;91(6):2225-31. doi: 10.1210/jc.2006-0235. Epub 2006 Mar 21. J Clin Endocrinol Metab. 2006. PMID: 16551736
Expression of functional KISS1 and KISS1R system is altered in human pituitary adenomas: evidence for apoptotic action of kisspeptin-10.
Martínez-Fuentes AJ, Molina M, Vázquez-Martínez R, Gahete MD, Jiménez-Reina L, Moreno-Fernández J, Benito-López P, Quintero A, de la Riva A, Diéguez C, Soto A, Leal-Cerro A, Resmini E, Webb SM, Zatelli MC, degli Uberti EC, Malagón MM, Luque RM, Castaño JP. Martínez-Fuentes AJ, et al. Eur J Endocrinol. 2011 Mar;164(3):355-62. doi: 10.1530/EJE-10-0905. Epub 2010 Dec 17. Eur J Endocrinol. 2011. PMID: 21169415
54 results