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The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.
Hu L, van der Hoogt CC, Espirito Santo SM, Out R, Kypreos KE, van Vlijmen BJ, Van Berkel TJ, Romijn JA, Havekes LM, van Dijk KW, Rensen PC. Hu L, et al. Among authors: van vlijmen bj, van der hoogt cc, van dijk kw, van berkel tj. J Lipid Res. 2008 Jul;49(7):1553-61. doi: 10.1194/jlr.M800130-JLR200. Epub 2008 Mar 26. J Lipid Res. 2008. PMID: 18367731 Free article.
Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice.
van Vlijmen BJ, van 't Hof HB, Mol MJ, van der Boom H, van der Zee A, Frants RR, Hofker MH, Havekes LM. van Vlijmen BJ, et al. Among authors: van der boom h, van t hof hb, van der zee a. J Clin Invest. 1996 Mar 1;97(5):1184-92. doi: 10.1172/JCI118532. J Clin Invest. 1996. PMID: 8636429 Free PMC article.
In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 --> Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice.
van Vlijmen BJ, van Dijk KW, van't Hof HB, van Gorp PJ, van der Zee A, van der Boom H, Breuer ML, Hofker MH, Havekes LM. van Vlijmen BJ, et al. Among authors: van gorp pj, van dijk kw, van der boom h, van t hof hb, van der zee a. J Biol Chem. 1996 Nov 29;271(48):30595-602. doi: 10.1074/jbc.271.48.30595. J Biol Chem. 1996. PMID: 8940032 Free article.
Uptake by J774 macrophages of very-low-density lipoproteins isolated from apoE-deficient mice is mediated by a distinct receptor and stimulated by lipoprotein lipase.
Hendriks WL, van der Sman-de Beer F, van Vlijmen BJ, van Vark LC, Hofker MH, Havekes LM. Hendriks WL, et al. Among authors: van vlijmen bj, van der sman de beer f, van vark lc. Arterioscler Thromb Vasc Biol. 1997 Mar;17(3):498-504. doi: 10.1161/01.atv.17.3.498. Arterioscler Thromb Vasc Biol. 1997. PMID: 9102168
Use of transgenic mice in lipoprotein metabolism and atherosclerosis research.
Havekes LM, van Vlijmen BJ, Jong MC, van Dijk KW, Hofker MH. Havekes LM, et al. Among authors: van vlijmen bj, van dijk kw. Prostaglandins Leukot Essent Fatty Acids. 1997 Oct;57(4-5):463-6. doi: 10.1016/s0952-3278(97)90429-4. Prostaglandins Leukot Essent Fatty Acids. 1997. PMID: 9430397
Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor.
van Dijk KW, van Vlijmen BJ, van der Zee A, van't Hof B, van der Boom H, Kobayashi K, Chan L, Havekes LM, Hofker MH. van Dijk KW, et al. Among authors: van vlijmen bj, van der boom h, van der zee a, van t hof b. Arterioscler Thromb Vasc Biol. 1998 Jan;18(1):7-12. doi: 10.1161/01.atv.18.1.7. Arterioscler Thromb Vasc Biol. 1998. PMID: 9445249
93 results