Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

110 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Pharmacological characterisation of GSK3335103, an oral αvβ6 integrin small molecule RGD-mimetic inhibitor for the treatment of fibrotic disease.
Wilkinson AL, John AE, Barrett JW, Gower E, Morrison VS, Man Y, Pun KT, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Fisher AJ, Procopiou PA, Hatley RJD, Barrett TN, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. Wilkinson AL, et al. Among authors: borthwick la. Eur J Pharmacol. 2021 Dec 15;913:174618. doi: 10.1016/j.ejphar.2021.174618. Epub 2021 Nov 8. Eur J Pharmacol. 2021. PMID: 34762934
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis.
John AE, Graves RH, Pun KT, Vitulli G, Forty EJ, Mercer PF, Morrell JL, Barrett JW, Rogers RF, Hafeji M, Bibby LI, Gower E, Morrison VS, Man Y, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Le J, Flint DJ, Pyne S, Habgood A, Organ LA, Joseph C, Edwards-Pritchard RC, Maher TM, Fisher AJ, Gudmann NS, Leeming DJ, Chambers RC, Lukey PT, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. John AE, et al. Among authors: borthwick la. Nat Commun. 2020 Sep 16;11(1):4659. doi: 10.1038/s41467-020-18397-6. Nat Commun. 2020. PMID: 32938936 Free PMC article.
FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis.
Leslie J, Millar BJ, Del Carpio Pons A, Burgoyne RA, Frost JD, Barksby BS, Luli S, Scott J, Simpson AJ, Gauldie J, Murray LA, Finch DK, Carruthers AM, Ferguson J, Sleeman MA, Rider D, Howarth R, Fox C, Oakley F, Fisher AJ, Mann DA, Borthwick LA. Leslie J, et al. JCI Insight. 2020 Feb 27;5(4):e125937. doi: 10.1172/jci.insight.125937. JCI Insight. 2020. PMID: 32102985 Free PMC article.
Cytokine mediated tissue fibrosis.
Borthwick LA, Wynn TA, Fisher AJ. Borthwick LA, et al. Biochim Biophys Acta. 2013 Jul;1832(7):1049-60. doi: 10.1016/j.bbadis.2012.09.014. Epub 2012 Oct 6. Biochim Biophys Acta. 2013. PMID: 23046809 Free PMC article. Review.
Lung epithelial wound healing in health and disease.
Gardner A, Borthwick LA, Fisher AJ. Gardner A, et al. Expert Rev Respir Med. 2010 Oct;4(5):647-60. doi: 10.1586/ers.10.62. Expert Rev Respir Med. 2010. PMID: 20923342 Review.
110 results