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The beta-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke.
Thöne-Reineke C, Neumann C, Namsolleck P, Schmerbach K, Krikov M, Schefe JH, Lucht K, Hörtnagl H, Godes M, Müller S, Rumschüssel K, Funke-Kaiser H, Villringer A, Steckelings UM, Unger T. Thöne-Reineke C, et al. Among authors: schefe jh. J Hypertens. 2008 Dec;26(12):2426-35. doi: 10.1097/HJH.0b013e328313e403. J Hypertens. 2008. PMID: 19008722
The promyelocytic leukemia zinc finger (PLZF) protein exerts neuroprotective effects in neuronal cells and is dysregulated in experimental stroke.
Seidel K, Kirsch S, Lucht K, Zaade D, Reinemund J, Schmitz J, Klare S, Li Y, Schefe JH, Schmerbach K, Goldin-Lang P, Zollmann FS, Thöne-Reineke C, Unger T, Funke-Kaiser H. Seidel K, et al. Among authors: schefe jh. Brain Pathol. 2011 Jan;21(1):31-43. doi: 10.1111/j.1750-3639.2010.00427.x. Brain Pathol. 2011. PMID: 20731660 Free PMC article.
PLZF and the (pro)renin receptor.
Schefe JH, Unger T, Funke-Kaiser H. Schefe JH, et al. J Mol Med (Berl). 2008 Jun;86(6):623-7. doi: 10.1007/s00109-008-0320-8. Epub 2008 Mar 12. J Mol Med (Berl). 2008. PMID: 18335187 Review.
A polymorphic microsatellite repeat within the ECE-1c promoter is involved in transcriptional start site determination, human evolution, and Alzheimer's disease.
Li Y, Seidel K, Marschall P, Klein M, Hope A, Schacherl J, Schmitz J, Menk M, Schefe JH, Reinemund J, Hugel R, Walden P, Schlosser A, Volkmer R, Schimkus J, Kölsch H, Maier W, Kornhuber J, Frölich L, Klare S, Kirsch S, Schmerbach K, Scheele S, Grittner U, Zollmann F, Goldin-Lang P, Peters O, Kintscher U, Unger T, Funke-Kaiser H. Li Y, et al. Among authors: schefe jh. J Neurosci. 2012 Nov 21;32(47):16807-20. doi: 10.1523/JNEUROSCI.2636-12.2012. J Neurosci. 2012. PMID: 23175834 Free PMC article.
17 results