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Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137.
Hombrouck A, Voet A, Van Remoortel B, Desadeleer C, De Maeyer M, Debyser Z, Witvrouw M. Hombrouck A, et al. Among authors: debyser z. Antimicrob Agents Chemother. 2008 Jun;52(6):2069-78. doi: 10.1128/AAC.00911-07. Epub 2008 Mar 31. Antimicrob Agents Chemother. 2008. PMID: 18378713 Free PMC article.
Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event.
De Clercq E, Yamamoto N, Pauwels R, Baba M, Schols D, Nakashima H, Balzarini J, Debyser Z, Murrer BA, Schwartz D, et al. De Clercq E, et al. Among authors: debyser z. Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5286-90. doi: 10.1073/pnas.89.12.5286. Proc Natl Acad Sci U S A. 1992. PMID: 1608936 Free PMC article.
New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs.
Pauwels R, Andries K, Debyser Z, Kukla MJ, Schols D, Breslin HJ, Woestenborghs R, Desmyter J, Janssen MA, De Clercq E, et al. Pauwels R, et al. Among authors: debyser z. Antimicrob Agents Chemother. 1994 Dec;38(12):2863-70. doi: 10.1128/AAC.38.12.2863. Antimicrob Agents Chemother. 1994. PMID: 7535037 Free PMC article.
Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase.
Pauwels R, Andries K, Debyser Z, Van Daele P, Schols D, Stoffels P, De Vreese K, Woestenborghs R, Vandamme AM, Janssen CG, et al. Pauwels R, et al. Among authors: debyser z. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1711-5. doi: 10.1073/pnas.90.5.1711. Proc Natl Acad Sci U S A. 1993. PMID: 7680476 Free PMC article.
Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100.
De Clercq E, Yamamoto N, Pauwels R, Balzarini J, Witvrouw M, De Vreese K, Debyser Z, Rosenwirth B, Peichl P, Datema R, et al. De Clercq E, et al. Among authors: debyser z. Antimicrob Agents Chemother. 1994 Apr;38(4):668-74. doi: 10.1128/AAC.38.4.668. Antimicrob Agents Chemother. 1994. PMID: 7913308 Free PMC article.
Baba, D. Schols, H. Nakashima, J. Balzarini, Z. Debyser, B. A. Murrer, D. Schwartz, D. Thornton, G. Bridger, S. Fricker, G. Henson, M. ...
Baba, D. Schols, H. Nakashima, J. Balzarini, Z. Debyser, B. A. Murrer, D. Schwartz, D. Thornton, G. Bridger, S. Fricker, G. He …
SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus.
Witvrouw M, Balzarini J, Pannecouque C, Jhaumeer-Laulloo S, Esté JA, Schols D, Cherepanov P, Schmit JC, Debyser Z, Vandamme AM, Desmyter J, Ramadas SR, de Clercq E. Witvrouw M, et al. Among authors: debyser z. Antimicrob Agents Chemother. 1997 Feb;41(2):262-8. doi: 10.1128/AAC.41.2.262. Antimicrob Agents Chemother. 1997. PMID: 9021177 Free PMC article.
325 results