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CYP2A6 and the plasma level of 5-chloro-2, 4-dihydroxypyridine are determinants of the pharmacokinetic variability of tegafur and 5-fluorouracil, respectively, in Japanese patients with cancer given S-1.
Fujita K, Yamamoto W, Endo S, Endo H, Nagashima F, Ichikawa W, Tanaka R, Miya T, Araki K, Kodama K, Sunakawa Y, Narabayashi M, Miwa K, Ando Y, Akiyama Y, Kawara K, Kamataki T, Sasaki Y. Fujita K, et al. Among authors: kamataki t. Cancer Sci. 2008 May;99(5):1049-54. doi: 10.1111/j.1349-7006.2008.00773.x. Cancer Sci. 2008. PMID: 18380793 Free PMC article. Clinical Trial.
Preclinical approach for identifying drug interactions.
Kamataki T, Yokoi T, Fujita K, Ando Y. Kamataki T, et al. Cancer Chemother Pharmacol. 1998;42 Suppl:S50-3. doi: 10.1007/s002800051079. Cancer Chemother Pharmacol. 1998. PMID: 9750029 Review.
Genetic polymorphism of CYP2A6 in relation to cancer.
Kamataki T, Nunoya K, Sakai Y, Kushida H, Fujita K. Kamataki T, et al. Mutat Res. 1999 Jul 16;428(1-2):125-30. doi: 10.1016/s1383-5742(99)00040-x. Mutat Res. 1999. PMID: 10517986
Overexpression of CYP2A6 in human colorectal tumors.
Matsuda Y, Saoo K, Yamakawa K, Yokohira M, Suzuki S, Kuno T, Kamataki T, Imaida K. Matsuda Y, et al. Among authors: kamataki t. Cancer Sci. 2007 Oct;98(10):1582-5. doi: 10.1111/j.1349-7006.2007.00572.x. Epub 2007 Aug 7. Cancer Sci. 2007. PMID: 17683511 Free PMC article.
413 results