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Ninety-nine is not enough: molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region.
Kozísek M, Sasková KG, Rezácová P, Brynda J, van Maarseveen NM, De Jong D, Boucher CA, Kagan RM, Nijhuis M, Konvalinka J. Kozísek M, et al. Among authors: brynda j. J Virol. 2008 Jun;82(12):5869-78. doi: 10.1128/JVI.02325-07. Epub 2008 Apr 9. J Virol. 2008. PMID: 18400858 Free PMC article.
Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.
Lescar J, Brynda J, Rezacova P, Stouracova R, Riottot MM, Chitarra V, Fabry M, Horejsi M, Sedlacek J, Bentley GA. Lescar J, et al. Among authors: brynda j. Protein Sci. 1999 Dec;8(12):2686-96. doi: 10.1110/ps.8.12.2686. Protein Sci. 1999. PMID: 10631984 Free PMC article.
A distinct binding mode of a hydroxyethylamine isostere inhibitor of HIV-1 protease.
Dohnálek J, Hasek J, Dusková J, Petroková H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlácek J, Fábry M. Dohnálek J, et al. Among authors: brynda j. Acta Crystallogr D Biol Crystallogr. 2001 Mar;57(Pt 3):472-6. doi: 10.1107/s0907444900018928. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11223536
Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor.
Dohnálek J, Hasek J, Dusková J, Petroková H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlácek J, Fábry M. Dohnálek J, et al. Among authors: brynda j. J Med Chem. 2002 Mar 28;45(7):1432-8. doi: 10.1021/jm010979e. J Med Chem. 2002. PMID: 11906284
Inhibition of HIV protease by monoclonal antibodies.
Rezacova P, Brynda J, Fabry M, Horejsi M, Stouracova R, Lescar J, Chitarra V, Riottot MM, Sedlacek J, Bentley GA. Rezacova P, et al. Among authors: brynda j. J Mol Recognit. 2002 Sep-Oct;15(5):272-6. doi: 10.1002/jmr.587. J Mol Recognit. 2002. PMID: 12447903 Review.
123 results