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Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis.
Molenaar JJ, Koster J, Ebus ME, van Sluis P, Westerhout EM, de Preter K, Gisselsson D, Øra I, Speleman F, Caron HN, Versteeg R. Molenaar JJ, et al. Among authors: van sluis p. Genes Chromosomes Cancer. 2012 Jan;51(1):10-9. doi: 10.1002/gcc.20926. Epub 2011 Oct 27. Genes Chromosomes Cancer. 2012. PMID: 22034077
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.
Molenaar JJ, Domingo-Fernández R, Ebus ME, Lindner S, Koster J, Drabek K, Mestdagh P, van Sluis P, Valentijn LJ, van Nes J, Broekmans M, Haneveld F, Volckmann R, Bray I, Heukamp L, Sprüssel A, Thor T, Kieckbusch K, Klein-Hitpass L, Fischer M, Vandesompele J, Schramm A, van Noesel MM, Varesio L, Speleman F, Eggert A, Stallings RL, Caron HN, Versteeg R, Schulte JH. Molenaar JJ, et al. Among authors: van noesel mm, van nes j, van sluis p. Nat Genet. 2012 Nov;44(11):1199-206. doi: 10.1038/ng.2436. Epub 2012 Oct 7. Nat Genet. 2012. PMID: 23042116
A NOTCH3 transcriptional module induces cell motility in neuroblastoma.
van Nes J, Chan A, van Groningen T, van Sluis P, Koster J, Versteeg R. van Nes J, et al. Among authors: van groningen t, van sluis p. Clin Cancer Res. 2013 Jul 1;19(13):3485-94. doi: 10.1158/1078-0432.CCR-12-3021. Epub 2013 May 6. Clin Cancer Res. 2013. PMID: 23649002
53 results