Kirschner LS - Search Results

1

Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.

Nadella KS, Jones GN, Trimboli A, Stratakis CA, Leone G, Kirschner LS. Nadella KS, et al. Among authors: kirschner ls. Cancer Res. 2008 Apr 15;68(8):2671-7. doi: 10.1158/0008-5472.CAN-07-6002. Cancer Res. 2008. PMID: 18413734 Free PMC article.

2

Regulatory subunit type I-alpha of protein kinase A (PRKAR1A): a tumor-suppressor gene for sporadic thyroid cancer.

Sandrini F, Matyakhina L, Sarlis NJ, Kirschner LS, Farmakidis C, Gimm O, Stratakis CA. Sandrini F, et al. Among authors: kirschner ls. Genes Chromosomes Cancer. 2002 Oct;35(2):182-92. doi: 10.1002/gcc.10112. Genes Chromosomes Cancer. 2002. PMID: 12203783

3

Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors.

Griffin KJ, Kirschner LS, Matyakhina L, Stergiopoulos S, Robinson-White A, Lenherr S, Weinberg FD, Claflin E, Meoli E, Cho-Chung YS, Stratakis CA. Griffin KJ, et al. Among authors: kirschner ls. Cancer Res. 2004 Dec 15;64(24):8811-5. doi: 10.1158/0008-5472.CAN-04-3620. Cancer Res. 2004. PMID: 15604237

4

A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues.

Kirschner LS, Kusewitt DF, Matyakhina L, Towns WH 2nd, Carney JA, Westphal H, Stratakis CA. Kirschner LS, et al. Cancer Res. 2005 Jun 1;65(11):4506-14. doi: 10.1158/0008-5472.CAN-05-0580. Cancer Res. 2005. PMID: 15930266 Free article.

5

Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins.

Nadella KS, Kirschner LS. Nadella KS, et al. Among authors: kirschner ls. Cancer Res. 2005 Nov 15;65(22):10307-15. doi: 10.1158/0008-5472.CAN-05-3183. Cancer Res. 2005. PMID: 16288019

6

Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A.

Pavel E, Nadella K, Towns WH 2nd, Kirschner LS. Pavel E, et al. Among authors: kirschner ls. Mol Endocrinol. 2008 Feb;22(2):430-40. doi: 10.1210/me.2007-0369. Epub 2007 Oct 11. Mol Endocrinol. 2008. PMID: 17932105 Free PMC article.

7

Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.

Yin Z, Jones GN, Towns WH 2nd, Zhang X, Abel ED, Binkley PF, Jarjoura D, Kirschner LS. Yin Z, et al. Among authors: kirschner ls. Circulation. 2008 Mar 18;117(11):1414-22. doi: 10.1161/CIRCULATIONAHA.107.759233. Epub 2008 Mar 3. Circulation. 2008. PMID: 18316483

8

Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production.

Jones GN, Tep C, Towns WH 2nd, Mihai G, Tonks ID, Kay GF, Schmalbrock PM, Stemmer-Rachamimov AO, Yoon SO, Kirschner LS. Jones GN, et al. Among authors: kirschner ls. Neoplasia. 2008 Nov;10(11):1213-21. doi: 10.1593/neo.08652. Neoplasia. 2008. PMID: 18953430 Free PMC article.

9

Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1.

Nadella KS, Saji M, Jacob NK, Pavel E, Ringel MD, Kirschner LS. Nadella KS, et al. Among authors: kirschner ls. EMBO Rep. 2009 Jun;10(6):599-605. doi: 10.1038/embor.2009.58. Epub 2009 May 8. EMBO Rep. 2009. PMID: 19424295 Free PMC article.

10

Mouse models of altered protein kinase A signaling.

Kirschner LS, Yin Z, Jones GN, Mahoney E. Kirschner LS, et al. Endocr Relat Cancer. 2009 Sep;16(3):773-93. doi: 10.1677/ERC-09-0068. Epub 2009 May 26. Endocr Relat Cancer. 2009. PMID: 19470615 Review.

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