Rosenblum MG - Search Results

1

Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis.

Martínez-Torrecuadrada JL, Cheung LH, López-Serra P, Barderas R, Cañamero M, Ferreiro S, Rosenblum MG, Casal JI. Martínez-Torrecuadrada JL, et al. Among authors: rosenblum mg. Mol Cancer Ther. 2008 Apr;7(4):862-73. doi: 10.1158/1535-7163.MCT-07-0394. Mol Cancer Ther. 2008. PMID: 18413799

2

Design, expression, purification, and characterization, in vitro and in vivo, of an antimelanoma single-chain Fv antibody fused to the toxin gelonin.

Rosenblum MG, Cheung LH, Liu Y, Marks JW 3rd. Rosenblum MG, et al. Cancer Res. 2003 Jul 15;63(14):3995-4002. Cancer Res. 2003. PMID: 12873997

3

Mechanistic studies of a novel human fusion toxin composed of vascular endothelial growth factor (VEGF)121 and the serine protease granzyme B: directed apoptotic events in vascular endothelial cells.

Liu Y, Cheung LH, Thorpe P, Rosenblum MG. Liu Y, et al. Among authors: rosenblum mg. Mol Cancer Ther. 2003 Oct;2(10):949-59. Mol Cancer Ther. 2003. PMID: 14578460

4

Recombinant single-chain antibody fusion construct targeting human melanoma cells and containing tumor necrosis factor.

Liu Y, Cheung LH, Marks JW, Rosenblum MG. Liu Y, et al. Among authors: rosenblum mg. Int J Cancer. 2004 Feb 10;108(4):549-57. doi: 10.1002/ijc.11524. Int J Cancer. 2004. PMID: 14696119

5

Targeted delivery of human pro-apoptotic enzymes to tumor cells: In vitro studies describing a novel class of recombinant highly cytotoxic agents.

Liu Y, Cheung LH, Hittelman WN, Rosenblum MG. Liu Y, et al. Among authors: rosenblum mg. Mol Cancer Ther. 2003 Dec;2(12):1341-50. Mol Cancer Ther. 2003. PMID: 14707275

6

The rGel/BLyS fusion toxin specifically targets malignant B cells expressing the BLyS receptors BAFF-R, TACI, and BCMA.

Lyu MA, Cheung LH, Hittelman WN, Marks JW, Aguiar RC, Rosenblum MG. Lyu MA, et al. Among authors: rosenblum mg. Mol Cancer Ther. 2007 Feb;6(2):460-70. doi: 10.1158/1535-7163.MCT-06-0254. Epub 2007 Jan 31. Mol Cancer Ther. 2007. PMID: 17267661

7

Recombinant CPE fused to tumor necrosis factor targets human ovarian cancer cells expressing the claudin-3 and claudin-4 receptors.

Yuan X, Lin X, Manorek G, Kanatani I, Cheung LH, Rosenblum MG, Howell SB. Yuan X, et al. Among authors: rosenblum mg. Mol Cancer Ther. 2009 Jul;8(7):1906-15. doi: 10.1158/1535-7163.MCT-09-0106. Epub 2009 Jun 30. Mol Cancer Ther. 2009. PMID: 19567823

8

Construction and characterization of novel, recombinant immunotoxins targeting the Her2/neu oncogene product: in vitro and in vivo studies.

Cao Y, Marks JD, Marks JW, Cheung LH, Kim S, Rosenblum MG. Cao Y, et al. Among authors: rosenblum mg. Cancer Res. 2009 Dec 1;69(23):8987-95. doi: 10.1158/0008-5472.CAN-09-2693. Epub 2009 Nov 24. Cancer Res. 2009. PMID: 19934334

9

Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells.

Zhou H, Marks JW, Hittelman WN, Yagita H, Cheung LH, Rosenblum MG, Winkles JA. Zhou H, et al. Among authors: rosenblum mg. Mol Cancer Ther. 2011 Jul;10(7):1276-88. doi: 10.1158/1535-7163.MCT-11-0161. Epub 2011 May 17. Mol Cancer Ther. 2011. PMID: 21586630 Free PMC article.

10

Single-chain antibody-based immunotoxins targeting Her2/neu: design optimization and impact of affinity on antitumor efficacy and off-target toxicity.

Cao Y, Marks JD, Huang Q, Rudnick SI, Xiong C, Hittelman WN, Wen X, Marks JW, Cheung LH, Boland K, Li C, Adams GP, Rosenblum MG. Cao Y, et al. Among authors: rosenblum mg. Mol Cancer Ther. 2012 Jan;11(1):143-53. doi: 10.1158/1535-7163.MCT-11-0519. Epub 2011 Nov 16. Mol Cancer Ther. 2012. PMID: 22090420

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