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Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery.
Sgraja T, Alphey MS, Ghilagaber S, Marquez R, Robertson MN, Hemmings JL, Lauw S, Rohdich F, Bacher A, Eisenreich W, Illarionova V, Hunter WN. Sgraja T, et al. Among authors: eisenreich w. FEBS J. 2008 Jun;275(11):2779-94. doi: 10.1111/j.1742-4658.2008.06418.x. Epub 2008 Apr 16. FEBS J. 2008. PMID: 18422643 Free PMC article.
The identification of isoprenoids that bind in the intersubunit cavity of Escherichia coli 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase by complementary biophysical methods.
Kemp LE, Alphey MS, Bond CS, Ferguson MA, Hecht S, Bacher A, Eisenreich W, Rohdich F, Hunter WN. Kemp LE, et al. Among authors: eisenreich w. Acta Crystallogr D Biol Crystallogr. 2005 Jan;61(Pt 1):45-52. doi: 10.1107/S0907444904025971. Epub 2004 Dec 17. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 15608374
The crystal structure of a plant 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase exhibits a distinct quaternary structure compared to bacterial homologues and a possible role in feedback regulation for cytidine monophosphate.
Gabrielsen M, Kaiser J, Rohdich F, Eisenreich W, Laupitz R, Bacher A, Bond CS, Hunter WN. Gabrielsen M, et al. Among authors: eisenreich w. FEBS J. 2006 Mar;273(5):1065-73. doi: 10.1111/j.1742-4658.2006.05133.x. FEBS J. 2006. PMID: 16478479 Free article.
Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis.
Gabrielsen M, Bond CS, Hallyburton I, Hecht S, Bacher A, Eisenreich W, Rohdich F, Hunter WN. Gabrielsen M, et al. Among authors: eisenreich w. J Biol Chem. 2004 Dec 10;279(50):52753-61. doi: 10.1074/jbc.M408895200. Epub 2004 Oct 2. J Biol Chem. 2004. PMID: 15466439 Free article.
309 results