Simon MC - Search Results

1

Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism.

Young RM, Wang SJ, Gordan JD, Ji X, Liebhaber SA, Simon MC. Young RM, et al. Among authors: simon mc. J Biol Chem. 2008 Jun 13;283(24):16309-19. doi: 10.1074/jbc.M710079200. Epub 2008 Apr 22. J Biol Chem. 2008. PMID: 18430730 Free PMC article.

2

Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription.

Arsham AM, Plas DR, Thompson CB, Simon MC. Arsham AM, et al. Among authors: simon mc. J Biol Chem. 2002 Apr 26;277(17):15162-70. doi: 10.1074/jbc.M111162200. Epub 2002 Feb 21. J Biol Chem. 2002. PMID: 11859074 Free article.

3

A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

Arsham AM, Howell JJ, Simon MC. Arsham AM, et al. Among authors: simon mc. J Biol Chem. 2003 Aug 8;278(32):29655-60. doi: 10.1074/jbc.M212770200. Epub 2003 May 30. J Biol Chem. 2003. PMID: 12777372 Free article.

4

Regulation of transcription and translation by hypoxia.

Liu L, Simon MC. Liu L, et al. Among authors: simon mc. Cancer Biol Ther. 2004 Jun;3(6):492-7. doi: 10.4161/cbt.3.6.1010. Epub 2004 Jun 8. Cancer Biol Ther. 2004. PMID: 15254394 Free article. Review.

5

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation.

Mansfield KD, Guzy RD, Pan Y, Young RM, Cash TP, Schumacker PT, Simon MC. Mansfield KD, et al. Among authors: simon mc. Cell Metab. 2005 Jun;1(6):393-9. doi: 10.1016/j.cmet.2005.05.003. Cell Metab. 2005. PMID: 16054088 Free PMC article.

6

Hypoxia-induced energy stress regulates mRNA translation and cell growth.

Liu L, Cash TP, Jones RG, Keith B, Thompson CB, Simon MC. Liu L, et al. Among authors: simon mc. Mol Cell. 2006 Feb 17;21(4):521-31. doi: 10.1016/j.molcel.2006.01.010. Mol Cell. 2006. PMID: 16483933 Free PMC article.

7

cGMP-dependent protein kinase phosphorylates p21-activated kinase (Pak) 1, inhibiting Pak/Nck binding and stimulating Pak/vasodilator-stimulated phosphoprotein association.

Fryer BH, Wang C, Vedantam S, Zhou GL, Jin S, Fletcher L, Simon MC, Field J. Fryer BH, et al. Among authors: simon mc. J Biol Chem. 2006 Apr 28;281(17):11487-95. doi: 10.1074/jbc.M600279200. Epub 2006 Feb 20. J Biol Chem. 2006. PMID: 16490784 Free article.

8

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B. Covello KL, et al. Among authors: simon mc. Genes Dev. 2006 Mar 1;20(5):557-70. doi: 10.1101/gad.1399906. Genes Dev. 2006. PMID: 16510872 Free PMC article.

9

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest.

Zhang F, Hamanaka RB, Bobrovnikova-Marjon E, Gordan JD, Dai MS, Lu H, Simon MC, Diehl JA. Zhang F, et al. Among authors: simon mc. J Biol Chem. 2006 Oct 6;281(40):30036-45. doi: 10.1074/jbc.M604674200. Epub 2006 Aug 7. J Biol Chem. 2006. PMID: 16893887 Free article.

10

Hypoxia-inducible factors: central regulators of the tumor phenotype.

Gordan JD, Simon MC. Gordan JD, et al. Among authors: simon mc. Curr Opin Genet Dev. 2007 Feb;17(1):71-7. doi: 10.1016/j.gde.2006.12.006. Epub 2007 Jan 8. Curr Opin Genet Dev. 2007. PMID: 17208433 Free PMC article. Review.

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