Okamura T - Search Results

1

Combined ascorbic acid and sodium nitrite treatment induces oxidative DNA damage-associated mutagenicity in vitro, but lacks initiation activity in rat forestomach epithelium.

Kuroiwa Y, Yamada M, Matsui K, Okamura T, Ishii Y, Masumura K, Tasaki M, Umemura T, Mitsumori K, Nohmi T, Hirose M, Nishikawa A. Kuroiwa Y, et al. Among authors: okamura t. Toxicol Sci. 2008 Aug;104(2):274-82. doi: 10.1093/toxsci/kfn081. Epub 2008 Apr 22. Toxicol Sci. 2008. PMID: 18434339

2

Detection of oxidative DNA damage, cell proliferation and in vivo mutagenicity induced by dicyclanil, a non-genotoxic carcinogen, using gpt delta mice.

Umemura T, Kuroiwa Y, Tasaki M, Okamura T, Ishii Y, Kodama Y, Nohmi T, Mitsumori K, Nishikawa A, Hirose M. Umemura T, et al. Among authors: okamura t. Mutat Res. 2007 Sep 1;633(1):46-54. doi: 10.1016/j.mrgentox.2007.05.007. Epub 2007 May 18. Mutat Res. 2007. PMID: 17581771

3

Enhancement of esophageal carcinogenesis in acid reflux model rats treated with ascorbic acid and sodium nitrite in combination with or without initiation.

Kuroiwa Y, Okamura T, Ishii Y, Umemura T, Tasaki M, Kanki K, Mitsumori K, Hirose M, Nishikawa A. Kuroiwa Y, et al. Among authors: okamura t. Cancer Sci. 2008 Jan;99(1):7-13. doi: 10.1111/j.1349-7006.2007.00649.x. Epub 2007 Oct 22. Cancer Sci. 2008. PMID: 17953708 Free PMC article.

4

beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats.

Dewa Y, Nishimura J, Muguruma M, Jin M, Saegusa Y, Okamura T, Tasaki M, Umemura T, Mitsumori K. Dewa Y, et al. Among authors: okamura t. Toxicology. 2008 Feb 28;244(2-3):179-89. doi: 10.1016/j.tox.2007.11.010. Epub 2007 Nov 22. Toxicology. 2008. PMID: 18164116

5

Induction of characteristic hepatocyte proliferative lesion with dietary exposure of Wistar Hannover rats to tocotrienol for 1 year.

Tasaki M, Umemura T, Inoue T, Okamura T, Kuroiwa Y, Ishii Y, Maeda M, Hirose M, Nishikawa A. Tasaki M, et al. Among authors: okamura t. Toxicology. 2008 Sep 4;250(2-3):143-50. doi: 10.1016/j.tox.2008.07.003. Epub 2008 Jul 15. Toxicology. 2008. PMID: 18675878

6

Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats.

Dewa Y, Nishimura J, Muguruma M, Jin M, Kawai M, Saegusa Y, Okamura T, Umemura T, Mitsumori K. Dewa Y, et al. Among authors: okamura t. Arch Toxicol. 2009 May;83(5):503-11. doi: 10.1007/s00204-008-0349-z. Epub 2008 Aug 27. Arch Toxicol. 2009. PMID: 18754104

7

Role of Nrf2 and oxidative stress on fenofibrate-induced hepatocarcinogenesis in rats.

Nishimura J, Dewa Y, Okamura T, Jin M, Saegusa Y, Kawai M, Umemura T, Shibutani M, Mitsumori K. Nishimura J, et al. Among authors: okamura t. Toxicol Sci. 2008 Dec;106(2):339-49. doi: 10.1093/toxsci/kfn174. Epub 2008 Sep 4. Toxicol Sci. 2008. PMID: 18775883

8

Possible participation of oxidative stress in causation of cell proliferation and in vivo mutagenicity in kidneys of gpt delta rats treated with potassium bromate.

Umemura T, Tasaki M, Kijima A, Okamura T, Inoue T, Ishii Y, Suzuki Y, Masui N, Nohmi T, Nishikawa A. Umemura T, et al. Among authors: okamura t. Toxicology. 2009 Mar 4;257(1-2):46-52. doi: 10.1016/j.tox.2008.12.007. Epub 2008 Dec 14. Toxicology. 2009. PMID: 19133310

9

Dietary catechol causes increased oxidative DNA damage in the livers of mice treated with acetaminophen.

Ishii Y, Okamura T, Inoue T, Tasaki M, Umemura T, Nishikawa A. Ishii Y, et al. Among authors: okamura t. Toxicology. 2009 Sep 19;263(2-3):93-9. doi: 10.1016/j.tox.2009.06.022. Epub 2009 Jul 2. Toxicology. 2009. PMID: 19576946

10

Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non-genotoxic hepatocarcinogens with cytochrome P450-inducible potency.

Tasaki M, Umemura T, Suzuki Y, Hibi D, Inoue T, Okamura T, Ishii Y, Maruyama S, Nohmi T, Nishikawa A. Tasaki M, et al. Among authors: okamura t. Cancer Sci. 2010 Dec;101(12):2525-30. doi: 10.1111/j.1349-7006.2010.01705.x. Cancer Sci. 2010. PMID: 20735435 Free PMC article.

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