Ellman JA - Search Results

1

Identification of a new class of nonpeptidic inhibitors of cruzain.

Brak K, Doyle PS, McKerrow JH, Ellman JA. Brak K, et al. Among authors: ellman ja. J Am Chem Soc. 2008 May 21;130(20):6404-10. doi: 10.1021/ja710254m. Epub 2008 Apr 25. J Am Chem Soc. 2008. PMID: 18435536 Free PMC article.

2

Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II.

Haque TS, Skillman AG, Lee CE, Habashita H, Gluzman IY, Ewing TJ, Goldberg DE, Kuntz ID, Ellman JA. Haque TS, et al. Among authors: ellman ja. J Med Chem. 1999 Apr 22;42(8):1428-40. doi: 10.1021/jm980641t. J Med Chem. 1999. PMID: 10212129

3

Annulation of aromatic imines via directed C-H activation with Wilkinson's catalyst.

Thalji RK, Ahrendt KA, Bergman RG, Ellman JA. Thalji RK, et al. Among authors: ellman ja. J Am Chem Soc. 2001 Oct 3;123(39):9692-3. doi: 10.1021/ja016642j. J Am Chem Soc. 2001. PMID: 11572698 No abstract available.

4

Design, synthesis, and utility of a support-bound tert-butanesulfinamide.

Dragoli DR, Burdett MT, Ellman JA. Dragoli DR, et al. Among authors: ellman ja. J Am Chem Soc. 2001 Oct 17;123(41):10127-8. doi: 10.1021/ja016349j. J Am Chem Soc. 2001. PMID: 11592904 No abstract available.

5

Parallel solution-phase synthesis of mechanism-based cysteine protease inhibitors.

Lee A, Ellman JA. Lee A, et al. Among authors: ellman ja. Org Lett. 2001 Nov 15;3(23):3707-9. doi: 10.1021/ol0166496. Org Lett. 2001. PMID: 11700118

6

Identification of potent and selective mechanism-based inhibitors of the cysteine protease cruzain using solid-phase parallel synthesis.

Huang L, Lee A, Ellman JA. Huang L, et al. Among authors: ellman ja. J Med Chem. 2002 Jan 31;45(3):676-84. doi: 10.1021/jm010333m. J Med Chem. 2002. PMID: 11806719

7

Asymmetric synthesis of syn- and anti-1,3-amino alcohols.

Kochi T, Tang TP, Ellman JA. Kochi T, et al. Among authors: ellman ja. J Am Chem Soc. 2002 Jun 12;124(23):6518-9. doi: 10.1021/ja026292g. J Am Chem Soc. 2002. PMID: 12047156

8

General solid-phase method to prepare novel cyclic ketone inhibitors of the cysteine protease cruzain.

Huang L, Ellman JA. Huang L, et al. Among authors: ellman ja. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2993-6. doi: 10.1016/s0960-894x(02)00619-4. Bioorg Med Chem Lett. 2002. PMID: 12270191

9

Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain.

Huang L, Brinen LS, Ellman JA. Huang L, et al. Among authors: ellman ja. Bioorg Med Chem. 2003 Jan 2;11(1):21-9. doi: 10.1016/s0968-0896(02)00427-3. Bioorg Med Chem. 2003. PMID: 12467703

10

Peptide microarrays for the determination of protease substrate specificity.

Salisbury CM, Maly DJ, Ellman JA. Salisbury CM, et al. Among authors: ellman ja. J Am Chem Soc. 2002 Dec 18;124(50):14868-70. doi: 10.1021/ja027477q. J Am Chem Soc. 2002. PMID: 12475327

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