Fesik S - Search Results

1

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor.

Tse C, Shoemaker AR, Adickes J, Anderson MG, Chen J, Jin S, Johnson EF, Marsh KC, Mitten MJ, Nimmer P, Roberts L, Tahir SK, Xiao Y, Yang X, Zhang H, Fesik S, Rosenberg SH, Elmore SW. Tse C, et al. Among authors: fesik s. Cancer Res. 2008 May 1;68(9):3421-8. doi: 10.1158/0008-5472.CAN-07-5836. Cancer Res. 2008. PMID: 18451170

2

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP.

Sun C, Cai M, Gunasekera AH, Meadows RP, Wang H, Chen J, Zhang H, Wu W, Xu N, Ng SC, Fesik SW. Sun C, et al. Among authors: fesik sw. Nature. 1999 Oct 21;401(6755):818-22. doi: 10.1038/44617. Nature. 1999. PMID: 10548111

3

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.

Petros AM, Nettesheim DG, Wang Y, Olejniczak ET, Meadows RP, Mack J, Swift K, Matayoshi ED, Zhang H, Thompson CB, Fesik SW. Petros AM, et al. Among authors: fesik sw. Protein Sci. 2000 Dec;9(12):2528-34. doi: 10.1110/ps.9.12.2528. Protein Sci. 2000. PMID: 11206074 Free PMC article.

4

Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents.

Xiao Z, Chen Z, Gunasekera AH, Sowin TJ, Rosenberg SH, Fesik S, Zhang H. Xiao Z, et al. Among authors: fesik s. J Biol Chem. 2003 Jun 13;278(24):21767-73. doi: 10.1074/jbc.M300229200. Epub 2003 Apr 3. J Biol Chem. 2003. PMID: 12676925 Free article.

5

Human Chk1 expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.

Chen Z, Xiao Z, Chen J, Ng SC, Sowin T, Sham H, Rosenberg S, Fesik S, Zhang H. Chen Z, et al. Among authors: fesik s. Mol Cancer Ther. 2003 Jun;2(6):543-8. Mol Cancer Ther. 2003. PMID: 12813133

6

Structural biology of the Bcl-2 family of proteins.

Petros AM, Olejniczak ET, Fesik SW. Petros AM, et al. Biochim Biophys Acta. 2004 Mar 1;1644(2-3):83-94. doi: 10.1016/j.bbamcr.2003.08.012. Biochim Biophys Acta. 2004. PMID: 14996493 Free article. Review.

7

Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer.

Oost TK, Sun C, Armstrong RC, Al-Assaad AS, Betz SF, Deckwerth TL, Ding H, Elmore SW, Meadows RP, Olejniczak ET, Oleksijew A, Oltersdorf T, Rosenberg SH, Shoemaker AR, Tomaselli KJ, Zou H, Fesik SW. Oost TK, et al. J Med Chem. 2004 Aug 26;47(18):4417-26. doi: 10.1021/jm040037k. J Med Chem. 2004. PMID: 15317454

8

Development of a tightly regulated U6 promoter for shRNA expression.

Lin X, Yang J, Chen J, Gunasekera A, Fesik SW, Shen Y. Lin X, et al. FEBS Lett. 2004 Nov 19;577(3):376-80. doi: 10.1016/j.febslet.2004.10.033. FEBS Lett. 2004. PMID: 15556613 Free article.

9

Non-peptidic small molecule inhibitors of XIAP.

Park CM, Sun C, Olejniczak ET, Wilson AE, Meadows RP, Betz SF, Elmore SW, Fesik SW. Park CM, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):771-5. doi: 10.1016/j.bmcl.2004.11.010. Bioorg Med Chem Lett. 2005. PMID: 15664855

10

An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, Bruncko M, Deckwerth TL, Dinges J, Hajduk PJ, Joseph MK, Kitada S, Korsmeyer SJ, Kunzer AR, Letai A, Li C, Mitten MJ, Nettesheim DG, Ng S, Nimmer PM, O'Connor JM, Oleksijew A, Petros AM, Reed JC, Shen W, Tahir SK, Thompson CB, Tomaselli KJ, Wang B, Wendt MD, Zhang H, Fesik SW, Rosenberg SH. Oltersdorf T, et al. Among authors: fesik sw. Nature. 2005 Jun 2;435(7042):677-81. doi: 10.1038/nature03579. Epub 2005 May 15. Nature. 2005. PMID: 15902208 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

239 results

Search Page

Filters