Truong AP - Search Results

1

Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: bryostatin look-alikes that mimic phorbol ester function.

Keck GE, Kraft MB, Truong AP, Li W, Sanchez CC, Kedei N, Lewin NE, Blumberg PM. Keck GE, et al. Among authors: truong ap. J Am Chem Soc. 2008 May 28;130(21):6660-1. doi: 10.1021/ja8022169. Epub 2008 May 2. J Am Chem Soc. 2008. PMID: 18452293 Free PMC article.

2

Synthetic studies on the bryostatins: preparation of a truncated BC-ring intermediate by pyran annulation.

Keck GE, Truong AP. Keck GE, et al. Among authors: truong ap. Org Lett. 2005 May 26;7(11):2149-52. doi: 10.1021/ol050511w. Org Lett. 2005. PMID: 15901156 Free PMC article.

3

Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core.

Keck GE, Truong AP. Keck GE, et al. Among authors: truong ap. Org Lett. 2005 May 26;7(11):2153-6. doi: 10.1021/ol050512o. Org Lett. 2005. PMID: 15901157 Free PMC article.

4

Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters.

Keck GE, Poudel YB, Welch DS, Kraft MB, Truong AP, Stephens JC, Kedei N, Lewin NE, Blumberg PM. Keck GE, et al. Among authors: truong ap. Org Lett. 2009 Feb 5;11(3):593-6. doi: 10.1021/ol8027253. Org Lett. 2009. PMID: 19113896 Free PMC article.

5

Directed reduction of beta-amino ketones to syn or anti 1,3-amino alcohol derivatives.

Keck GE, Truong AP. Keck GE, et al. Among authors: truong ap. Org Lett. 2002 Sep 5;4(18):3131-4. doi: 10.1021/ol026456y. Org Lett. 2002. PMID: 12201734 Free PMC article.

6

Synthesis of a 2,3';6',3''-terpyridine scaffold as an alpha-helix mimetic.

Davis JM, Truong A, Hamilton AD. Davis JM, et al. Org Lett. 2005 Nov 24;7(24):5405-8. doi: 10.1021/ol0521228. Org Lett. 2005. PMID: 16288517

7

Triazolopyridazine LRRK2 kinase inhibitors.

Franzini M, Ye XM, Adler M, Aubele DL, Garofalo AW, Gauby S, Goldbach E, Probst GD, Quinn KP, Santiago P, Sham HL, Tam D, Truong A, Ren Z. Franzini M, et al. Bioorg Med Chem Lett. 2013 Apr 1;23(7):1967-73. doi: 10.1016/j.bmcl.2013.02.043. Epub 2013 Feb 14. Bioorg Med Chem Lett. 2013. PMID: 23454015

8

N-Bridged bicyclic sulfonamides as inhibitors of gamma-secretase.

Bowers S, Probst GD, Truong AP, Hom RK, Konradi AW, Sham HL, Garofalo AW, Wong K, Goldbach E, Quinn KP, Sauer JM, Wallace W, Nguyen L, Hemphill SS, Bova MP, Basi GS. Bowers S, et al. Among authors: truong ap. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6952-6. doi: 10.1016/j.bmcl.2009.10.060. Epub 2009 Oct 30. Bioorg Med Chem Lett. 2009. PMID: 19879755

9

Discovery of 4-alkylamino-7-aryl-3-cyanoquinoline LRRK2 kinase inhibitors.

Garofalo AW, Adler M, Aubele DL, Brigham EF, Chian D, Franzini M, Goldbach E, Kwong GT, Motter R, Probst GD, Quinn KP, Ruslim L, Sham HL, Tam D, Tanaka P, Truong AP, Ye XM, Ren Z. Garofalo AW, et al. Among authors: truong ap. Bioorg Med Chem Lett. 2013 Apr 1;23(7):1974-7. doi: 10.1016/j.bmcl.2013.02.041. Epub 2013 Feb 15. Bioorg Med Chem Lett. 2013. PMID: 23453068

10

Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model.

Truong AP, Tóth G, Probst GD, Sealy JM, Bowers S, Wone DW, Dressen D, Hom RK, Konradi AW, Sham HL, Wu J, Peterson BT, Ruslim L, Bova MP, Kholodenko D, Motter RN, Bard F, Santiago P, Ni H, Chian D, Soriano F, Cole T, Brigham EF, Wong K, Zmolek W, Goldbach E, Samant B, Chen L, Zhang H, Nakamura DF, Quinn KP, Yednock TA, Sauer JM. Truong AP, et al. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6231-6. doi: 10.1016/j.bmcl.2010.08.102. Epub 2010 Aug 24. Bioorg Med Chem Lett. 2010. PMID: 20833041

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