Xie F - Search Results

1

Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity.

Fang C, Gu J, Xie F, Behr M, Yang W, Abel ED, Ding X. Fang C, et al. Among authors: xie f. Drug Metab Dispos. 2008 Aug;36(8):1722-8. doi: 10.1124/dmd.108.021881. Epub 2008 May 7. Drug Metab Dispos. 2008. PMID: 18463197 Free PMC article.

2

Essential role of the cytochrome P450 enzyme CYP2A5 in olfactory mucosal toxicity of naphthalene.

Hu J, Sheng L, Li L, Zhou X, Xie F, D'Agostino J, Li Y, Ding X. Hu J, et al. Among authors: xie f. Drug Metab Dispos. 2014 Jan;42(1):23-7. doi: 10.1124/dmd.113.054429. Epub 2013 Oct 8. Drug Metab Dispos. 2014. PMID: 24104196 Free PMC article.

3

A mouse model with liver-specific deletion and global suppression of the NADPH-cytochrome P450 reductase gene: characterization and utility for in vivo studies of cyclophosphamide disposition.

Gu J, Chen CS, Wei Y, Fang C, Xie F, Kannan K, Yang W, Waxman DJ, Ding X. Gu J, et al. Among authors: xie f. J Pharmacol Exp Ther. 2007 Apr;321(1):9-17. doi: 10.1124/jpet.106.118240. Epub 2007 Jan 11. J Pharmacol Exp Ther. 2007. PMID: 17218484

4

Mechanism of chloroform-induced renal toxicity: non-involvement of hepatic cytochrome P450-dependent metabolism.

Fang C, Behr M, Xie F, Lu S, Doret M, Luo H, Yang W, Aldous K, Ding X, Gu J. Fang C, et al. Among authors: xie f. Toxicol Appl Pharmacol. 2008 Feb 15;227(1):48-55. doi: 10.1016/j.taap.2007.10.014. Epub 2007 Oct 23. Toxicol Appl Pharmacol. 2008. PMID: 18031782 Free PMC article.

5

The tissue-specific toxicity of methimazole in the mouse olfactory mucosa is partly mediated through target-tissue metabolic activation by CYP2A5.

Xie F, Zhou X, Genter MB, Behr M, Gu J, Ding X. Xie F, et al. Drug Metab Dispos. 2011 Jun;39(6):947-51. doi: 10.1124/dmd.110.037895. Epub 2011 Mar 17. Drug Metab Dispos. 2011. PMID: 21415250 Free PMC article.

6

Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.

Megaraj V, Zhou X, Xie F, Liu Z, Yang W, Ding X. Megaraj V, et al. Among authors: xie f. Carcinogenesis. 2014 Jan;35(1):131-7. doi: 10.1093/carcin/bgt269. Epub 2013 Aug 5. Carcinogenesis. 2014. PMID: 23917075 Free PMC article.

7

Mice deficient in intestinal epithelium cytochrome P450 reductase are prone to acute toxin-induced mucosal damage.

Ahlawat S, Xie F, Zhu Y, D'Hondt R, Ding X, Zhang QY, Mantis NJ. Ahlawat S, et al. Among authors: xie f. Sci Rep. 2014 Jul 3;4:5551. doi: 10.1038/srep05551. Sci Rep. 2014. PMID: 24989705 Free PMC article.

8

Intestinal epithelium-specific knockout of the cytochrome P450 reductase gene exacerbates dextran sulfate sodium-induced colitis.

Zhu Y, Xie F, Ding L, Fan X, Ding X, Zhang QY. Zhu Y, et al. Among authors: xie f. J Pharmacol Exp Ther. 2015 Jul;354(1):10-7. doi: 10.1124/jpet.115.223263. Epub 2015 Apr 29. J Pharmacol Exp Ther. 2015. PMID: 25926522 Free PMC article.

9

Effect of Cytochrome P450 Reductase Deficiency on 2-Amino-9H-pyrido[2,3-b]indole Metabolism and DNA Adduct Formation in Liver and Extrahepatic Tissues of Mice.

Turesky RJ, Konorev D, Fan X, Tang Y, Yao L, Ding X, Xie F, Zhu Y, Zhang QY. Turesky RJ, et al. Among authors: xie f. Chem Res Toxicol. 2015 Dec 21;28(12):2400-10. doi: 10.1021/acs.chemrestox.5b00405. Epub 2015 Dec 3. Chem Res Toxicol. 2015. PMID: 26583703 Free PMC article.

10

An update on the role of intestinal cytochrome P450 enzymes in drug disposition.

Xie F, Ding X, Zhang QY. Xie F, et al. Acta Pharm Sin B. 2016 Sep;6(5):374-383. doi: 10.1016/j.apsb.2016.07.012. Epub 2016 Aug 4. Acta Pharm Sin B. 2016. PMID: 27709006 Free PMC article. Review.

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