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Computational redesign of protein-protein interaction specificity.
Kortemme T, Joachimiak LA, Bullock AN, Schuler AD, Stoddard BL, Baker D. Kortemme T, et al. Among authors: baker d. Nat Struct Mol Biol. 2004 Apr;11(4):371-9. doi: 10.1038/nsmb749. Epub 2004 Mar 21. Nat Struct Mol Biol. 2004. PMID: 15034550
A new twist in TCR diversity revealed by a forbidden alphabeta TCR.
McBeth C, Seamons A, Pizarro JC, Fleishman SJ, Baker D, Kortemme T, Goverman JM, Strong RK. McBeth C, et al. Among authors: baker d. J Mol Biol. 2008 Feb 1;375(5):1306-19. doi: 10.1016/j.jmb.2007.11.020. Epub 2007 Nov 17. J Mol Biol. 2008. PMID: 18155234 Free PMC article.
A de novo protein binding pair by computational design and directed evolution.
Karanicolas J, Corn JE, Chen I, Joachimiak LA, Dym O, Peck SH, Albeck S, Unger T, Hu W, Liu G, Delbecq S, Montelione GT, Spiegel CP, Liu DR, Baker D. Karanicolas J, et al. Among authors: baker d. Mol Cell. 2011 Apr 22;42(2):250-60. doi: 10.1016/j.molcel.2011.03.010. Epub 2011 Mar 31. Mol Cell. 2011. PMID: 21458342 Free PMC article.
Computational design of a protein-based enzyme inhibitor.
Procko E, Hedman R, Hamilton K, Seetharaman J, Fleishman SJ, Su M, Aramini J, Kornhaber G, Hunt JF, Tong L, Montelione GT, Baker D. Procko E, et al. Among authors: baker d. J Mol Biol. 2013 Sep 23;425(18):3563-75. doi: 10.1016/j.jmb.2013.06.035. Epub 2013 Jul 1. J Mol Biol. 2013. PMID: 23827138 Free PMC article.
A general computational approach for repeat protein design.
Parmeggiani F, Huang PS, Vorobiev S, Xiao R, Park K, Caprari S, Su M, Seetharaman J, Mao L, Janjua H, Montelione GT, Hunt J, Baker D. Parmeggiani F, et al. Among authors: baker d. J Mol Biol. 2015 Jan 30;427(2):563-75. doi: 10.1016/j.jmb.2014.11.005. Epub 2014 Nov 14. J Mol Biol. 2015. PMID: 25451037 Free PMC article.
5,820 results