Shire SJ - Search Results

1

Concluding summary: proceedings of the AAPS Biotec open forum on "aggregation of protein therapeutics".

Shire SJ, Cromwell M, Liu J. Shire SJ, et al. AAPS J. 2006;8(4):E729-30. doi: 10.1208/aapsj080482. AAPS J. 2006. PMID: 18473180 Free PMC article. No abstract available.

2

A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation.

Liu J, Andya JD, Shire SJ. Liu J, et al. Among authors: shire sj. AAPS J. 2006 Sep 22;8(3):E580-9. doi: 10.1208/aapsj080367. AAPS J. 2006. PMID: 17025276 Free PMC article. Review.

3

Characterization of particles in protein solutions: reaching the limits of current technologies.

Demeule B, Messick S, Shire SJ, Liu J. Demeule B, et al. Among authors: shire sj. AAPS J. 2010 Dec;12(4):708-15. doi: 10.1208/s12248-010-9233-x. Epub 2010 Oct 16. AAPS J. 2010. PMID: 20953747 Free PMC article.

4

Challenges in the development of high protein concentration formulations.

Shire SJ, Shahrokh Z, Liu J. Shire SJ, et al. J Pharm Sci. 2004 Jun;93(6):1390-402. doi: 10.1002/jps.20079. J Pharm Sci. 2004. PMID: 15124199 Review.

5

Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution.

Liu J, Nguyen MD, Andya JD, Shire SJ. Liu J, et al. Among authors: shire sj. J Pharm Sci. 2005 Sep;94(9):1928-40. doi: 10.1002/jps.20347. J Pharm Sci. 2005. PMID: 16052543

6

Analytical ultracentrifugation in the pharmaceutical industry.

Liu J, Shire SJ. Liu J, et al. Among authors: shire sj. J Pharm Sci. 1999 Dec;88(12):1237-41. doi: 10.1021/js9901458. J Pharm Sci. 1999. PMID: 10585216 Review. No abstract available.

7

Reversible self-association of a concentrated monoclonal antibody solution mediated by Fab-Fab interaction that impacts solution viscosity.

Kanai S, Liu J, Patapoff TW, Shire SJ. Kanai S, et al. Among authors: shire sj. J Pharm Sci. 2008 Oct;97(10):4219-27. doi: 10.1002/jps.21322. J Pharm Sci. 2008. PMID: 18240303

8

A therapeutic antibody and its antigen form different complexes in serum than in phosphate-buffered saline: a study by analytical ultracentrifugation.

Demeule B, Shire SJ, Liu J. Demeule B, et al. Among authors: shire sj. Anal Biochem. 2009 May 15;388(2):279-87. doi: 10.1016/j.ab.2009.03.012. Epub 2009 Mar 14. Anal Biochem. 2009. PMID: 19289095

9

Characteristics of rhVEGF release from topical hydrogel formulations.

Ji JA, Liu J, Shire SJ, Kamerzell TJ, Hong S, Billeci K, Shen Y, Wang YJ. Ji JA, et al. Among authors: shire sj. Pharm Res. 2010 Apr;27(4):644-54. doi: 10.1007/s11095-009-0039-4. Epub 2010 Feb 13. Pharm Res. 2010. PMID: 20155389

10

Intermolecular interactions of IgG1 monoclonal antibodies at high concentrations characterized by light scattering.

Scherer TM, Liu J, Shire SJ, Minton AP. Scherer TM, et al. Among authors: shire sj. J Phys Chem B. 2010 Oct 14;114(40):12948-57. doi: 10.1021/jp1028646. J Phys Chem B. 2010. PMID: 20849134

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