Hochalter JB - Search Results

1

Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphisms.

Hecht SS, Villalta PW, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Carcinogenesis. 2008 May;29(5):937-43. doi: 10.1093/carcin/bgn015. Epub 2008 May 13. Carcinogenesis. 2008. PMID: 18477646 Free PMC article.

2

Quantitation of enantiomers of r-7,t-8,9,c-10-tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]-pyrene in human urine: evidence supporting metabolic activation of benzo[a]pyrene via the bay region diol epoxide.

Hecht SS, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Mutagenesis. 2014 Sep;29(5):351-6. doi: 10.1093/mutage/geu024. Epub 2014 Jul 21. Mutagenesis. 2014. PMID: 25053834 Free PMC article.

3

Quantitation of N-acetyl-S-(9,10-dihydro-9-hydroxy-10-phenanthryl)-L-cysteine in human urine: comparison with glutathione-S-transferase genotypes in smokers.

Upadhyaya P, Rao P, Hochalter JB, Li ZZ, Villalta PW, Hecht SS. Upadhyaya P, et al. Among authors: hochalter jb. Chem Res Toxicol. 2006 Sep;19(9):1234-40. doi: 10.1021/tx060096w. Chem Res Toxicol. 2006. PMID: 16978029 Free PMC article.

4

Preferential glutathione conjugation of a reverse diol epoxide compared to a bay region diol epoxide of phenanthrene in human hepatocytes: relevance to molecular epidemiology studies of glutathione-s-transferase polymorphisms and cancer.

Hecht SS, Berg JZ, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Chem Res Toxicol. 2009 Mar 16;22(3):426-32. doi: 10.1021/tx800315m. Chem Res Toxicol. 2009. PMID: 19187038 Free PMC article.

5

Analysis of phenanthrene and benzo[a]pyrene tetraol enantiomers in human urine: relevance to the bay region diol epoxide hypothesis of benzo[a]pyrene carcinogenesis and to biomarker studies.

Hecht SS, Carmella SG, Villalta PW, Hochalter JB. Hecht SS, et al. Among authors: hochalter jb. Chem Res Toxicol. 2010 May 17;23(5):900-8. doi: 10.1021/tx9004538. Chem Res Toxicol. 2010. PMID: 20369855 Free PMC article.

6

Preferential glutathione conjugation of a reverse diol epoxide compared with a bay region diol epoxide of benzo[a]pyrene in human hepatocytes.

Upadhyaya P, Hochalter JB, Balbo S, McIntee EJ, Hecht SS. Upadhyaya P, et al. Among authors: hochalter jb. Drug Metab Dispos. 2010 Sep;38(9):1397-402. doi: 10.1124/dmd.110.034181. Epub 2010 Jun 14. Drug Metab Dispos. 2010. PMID: 20547966 Free PMC article.

7

Quantitation of a minor enantiomer of phenanthrene tetraol in human urine: correlations with levels of overall phenanthrene tetraol, benzo[a]pyrene tetraol, and 1-hydroxypyrene.

Hochalter JB, Zhong Y, Han S, Carmella SG, Hecht SS. Hochalter JB, et al. Chem Res Toxicol. 2011 Feb 18;24(2):262-8. doi: 10.1021/tx100391z. Epub 2011 Jan 13. Chem Res Toxicol. 2011. PMID: 21229973 Free PMC article.

8

Phenanthrene metabolism in smokers: use of a two-step diagnostic plot approach to identify subjects with extensive metabolic activation.

Wang J, Zhong Y, Carmella SG, Hochalter JB, Rauch D, Oliver A, Jensen J, Hatsukami DK, Upadhyaya P, Hecht SS, Zimmerman CL. Wang J, et al. Among authors: hochalter jb. J Pharmacol Exp Ther. 2012 Sep;342(3):750-60. doi: 10.1124/jpet.112.194118. Epub 2012 Jun 6. J Pharmacol Exp Ther. 2012. PMID: 22674470 Free PMC article. Clinical Trial.

9

Longitudinal study of [D10]phenanthrene metabolism by the diol epoxide pathway in smokers.

Hecht SS, Hochalter JB, Carmella SG, Zhang Y, Rauch DM, Fujioka N, Jensen J, Hatsukami DK. Hecht SS, et al. Among authors: hochalter jb. Biomarkers. 2013 Mar;18(2):144-50. doi: 10.3109/1354750X.2012.753553. Epub 2013 Jan 22. Biomarkers. 2013. PMID: 23336104 Free PMC article.

10

Methyl DNA phosphate adduct formation in lung tumor tissue and adjacent normal tissue of lung cancer patients.

Ma B, Villalta PW, Hochalter JB, Stepanov I, Hecht SS. Ma B, et al. Among authors: hochalter jb. Carcinogenesis. 2019 Nov 25;40(11):1387-1394. doi: 10.1093/carcin/bgz053. Carcinogenesis. 2019. PMID: 30873516 Free PMC article.

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