Sheppard D - Search Results

1

The alpha9beta1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel.

deHart GW, Jin T, McCloskey DE, Pegg AE, Sheppard D. deHart GW, et al. Among authors: sheppard d. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7188-93. doi: 10.1073/pnas.0708044105. Epub 2008 May 14. Proc Natl Acad Sci U S A. 2008. PMID: 18480266 Free PMC article.

2

The integrin alpha9beta1 mediates adhesion to activated endothelial cells and transendothelial neutrophil migration through interaction with vascular cell adhesion molecule-1.

Taooka Y, Chen J, Yednock T, Sheppard D. Taooka Y, et al. Among authors: sheppard d. J Cell Biol. 1999 Apr 19;145(2):413-20. doi: 10.1083/jcb.145.2.413. J Cell Biol. 1999. PMID: 10209034 Free PMC article.

3

Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis.

Kaminski N, Allard JD, Pittet JF, Zuo F, Griffiths MJ, Morris D, Huang X, Sheppard D, Heller RA. Kaminski N, et al. Among authors: sheppard d. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1778-83. doi: 10.1073/pnas.97.4.1778. Proc Natl Acad Sci U S A. 2000. PMID: 10677534 Free PMC article.

4

Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1.

Huang XZ, Wu JF, Ferrando R, Lee JH, Wang YL, Farese RV Jr, Sheppard D. Huang XZ, et al. Among authors: sheppard d. Mol Cell Biol. 2000 Jul;20(14):5208-15. doi: 10.1128/MCB.20.14.5208-5215.2000. Mol Cell Biol. 2000. PMID: 10866676 Free PMC article.

5

The cytoplasmic domain of the integrin alpha9 subunit requires the adaptor protein paxillin to inhibit cell spreading but promotes cell migration in a paxillin-independent manner.

Young BA, Taooka Y, Liu S, Askins KJ, Yokosaki Y, Thomas SM, Sheppard D. Young BA, et al. Among authors: sheppard d. Mol Biol Cell. 2001 Oct;12(10):3214-25. doi: 10.1091/mbc.12.10.3214. Mol Biol Cell. 2001. PMID: 11598204 Free PMC article.

6

Spermidine/spermine N1-acetyltransferase specifically binds to the integrin alpha9 subunit cytoplasmic domain and enhances cell migration.

Chen C, Young BA, Coleman CS, Pegg AE, Sheppard D. Chen C, et al. Among authors: sheppard d. J Cell Biol. 2004 Oct 11;167(1):161-70. doi: 10.1083/jcb.200312166. J Cell Biol. 2004. PMID: 15479742 Free PMC article.

7

The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1.

Vlahakis NE, Young BA, Atakilit A, Sheppard D. Vlahakis NE, et al. Among authors: sheppard d. J Biol Chem. 2005 Feb 11;280(6):4544-52. doi: 10.1074/jbc.M412816200. Epub 2004 Dec 6. J Biol Chem. 2005. PMID: 15590642 Free PMC article.

8

Integrin-mediated activation of latent transforming growth factor beta.

Sheppard D. Sheppard D. Cancer Metastasis Rev. 2005 Sep;24(3):395-402. doi: 10.1007/s10555-005-5131-6. Cancer Metastasis Rev. 2005. PMID: 16258727 Review.

9

Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix.

Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. Kim KK, et al. Among authors: sheppard d. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13180-5. doi: 10.1073/pnas.0605669103. Epub 2006 Aug 21. Proc Natl Acad Sci U S A. 2006. PMID: 16924102 Free PMC article.

10

The Integrin alpha9beta1 contributes to granulopoiesis by enhancing granulocyte colony-stimulating factor receptor signaling.

Chen C, Huang X, Atakilit A, Zhu QS, Corey SJ, Sheppard D. Chen C, et al. Among authors: sheppard d. Immunity. 2006 Dec;25(6):895-906. doi: 10.1016/j.immuni.2006.10.013. Epub 2006 Nov 30. Immunity. 2006. PMID: 17137800 Free article.

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