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Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.
Liu D, Cardozo AK, Darville MI, Eizirik DL. Liu D, et al. Among authors: eizirik dl. Endocrinology. 2002 Apr;143(4):1225-34. doi: 10.1210/endo.143.4.8737. Endocrinology. 2002. PMID: 11897677
Expression of adiponectin receptors in pancreatic beta cells.
Kharroubi I, Rasschaert J, Eizirik DL, Cnop M. Kharroubi I, et al. Among authors: eizirik dl. Biochem Biophys Res Commun. 2003 Dec 26;312(4):1118-22. doi: 10.1016/j.bbrc.2003.11.042. Biochem Biophys Res Commun. 2003. PMID: 14651988
T1DBase, a community web-based resource for type 1 diabetes research.
Smink LJ, Helton EM, Healy BC, Cavnor CC, Lam AC, Flamez D, Burren OS, Wang Y, Dolman GE, Burdick DB, Everett VH, Glusman G, Laneri D, Rowen L, Schuilenburg H, Walker NM, Mychaleckyj J, Wicker LS, Eizirik DL, Todd JA, Goodman N. Smink LJ, et al. Among authors: eizirik dl. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D544-9. doi: 10.1093/nar/gki095. Nucleic Acids Res. 2005. PMID: 15608258 Free PMC article.
Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.
Cardozo AK, Ortis F, Storling J, Feng YM, Rasschaert J, Tonnesen M, Van Eylen F, Mandrup-Poulsen T, Herchuelz A, Eizirik DL. Cardozo AK, et al. Among authors: eizirik dl. Diabetes. 2005 Feb;54(2):452-61. doi: 10.2337/diabetes.54.2.452. Diabetes. 2005. PMID: 15677503
430 results