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Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis.
Cnop M, Ladriere L, Hekerman P, Ortis F, Cardozo AK, Dogusan Z, Flamez D, Boyce M, Yuan J, Eizirik DL. Cnop M, et al. Among authors: ortis f. J Biol Chem. 2007 Feb 9;282(6):3989-97. doi: 10.1074/jbc.M607627200. Epub 2006 Dec 8. J Biol Chem. 2007. PMID: 17158450 Free article.
Loss of PPAR gamma in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue.
Guri AJ, Hontecillas R, Ferrer G, Casagran O, Wankhade U, Noble AM, Eizirik DL, Ortis F, Cnop M, Liu D, Si H, Bassaganya-Riera J. Guri AJ, et al. Among authors: ortis f. J Nutr Biochem. 2008 Apr;19(4):216-28. doi: 10.1016/j.jnutbio.2007.02.010. Epub 2007 Jul 6. J Nutr Biochem. 2008. PMID: 17618105
Cell-permeable peptides induce dose- and length-dependent cytotoxic effects.
Cardozo AK, Buchillier V, Mathieu M, Chen J, Ortis F, Ladrière L, Allaman-Pillet N, Poirot O, Kellenberger S, Beckmann JS, Eizirik DL, Bonny C, Maurer F. Cardozo AK, et al. Among authors: ortis f. Biochim Biophys Acta. 2007 Sep;1768(9):2222-34. doi: 10.1016/j.bbamem.2007.06.003. Epub 2007 Jun 14. Biochim Biophys Acta. 2007. PMID: 17626783 Free article.
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.
Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M. Cunha DA, et al. Among authors: ortis f. J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. doi: 10.1242/jcs.026062. Epub 2008 Jun 17. J Cell Sci. 2008. PMID: 18559892 Free PMC article.
44 results