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Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The first high affinity fluorescence probes for voltage-gated K+ channels.
Pragl B, Koschak A, Trieb M, Obermair G, Kaufmann WA, Gerster U, Blanc E, Hahn C, Prinz H, Schütz G, Darbon H, Gruber HJ, Knaus HG. Pragl B, et al. Among authors: koschak a. Bioconjug Chem. 2002 May-Jun;13(3):416-25. doi: 10.1021/bc015543s. Bioconjug Chem. 2002. PMID: 12009929
Hongotoxin(1) (HgTX(1)), a 39-residue peptide recently isolated from the venom of Centruroides limbatus, blocks the voltage-gated K+ channels K(v)1.1, K(v)1.2, and K(v)1.3 at picomolar toxin concentrations (Koschak, A., Bugianesi, R. ...In this report, we det …
Hongotoxin(1) (HgTX(1)), a 39-residue peptide recently isolated from the venom of Centruroides limbatus, blocks the voltage-gated K+ …
Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca 2+ channels.
Sinnegger-Brauns MJ, Hetzenauer A, Huber IG, Renström E, Wietzorrek G, Berjukov S, Cavalli M, Walter D, Koschak A, Waldschütz R, Hering S, Bova S, Rorsman P, Pongs O, Singewald N, Striessnig J. Sinnegger-Brauns MJ, et al. Among authors: koschak a. J Clin Invest. 2004 May;113(10):1430-9. doi: 10.1172/JCI20208. J Clin Invest. 2004. PMID: 15146240 Free PMC article.
L-type Ca2+ channels in Ca2+ channelopathies.
Striessnig J, Hoda JC, Koschak A, Zaghetto F, Müllner C, Sinnegger-Brauns MJ, Wild C, Watschinger K, Trockenbacher A, Pelster G. Striessnig J, et al. Among authors: koschak a. Biochem Biophys Res Commun. 2004 Oct 1;322(4):1341-6. doi: 10.1016/j.bbrc.2004.08.039. Biochem Biophys Res Commun. 2004. PMID: 15336981 Review.
45 results