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Using leucine zipper to facilitate alpha-synuclein assembly.
Jiang P, Ko LW, Jansen KR, Golde TE, Yen SH. Jiang P, et al. Among authors: golde te. FASEB J. 2008 Sep;22(9):3165-74. doi: 10.1096/fj.08-108365. Epub 2008 May 20. FASEB J. 2008. PMID: 18492724 Free PMC article.
Cell-free assays for gamma-secretase activity.
McLendon C, Xin T, Ziani-Cherif C, Murphy MP, Findlay KA, Lewis PA, Pinnix I, Sambamurti K, Wang R, Fauq A, Golde TE. McLendon C, et al. Among authors: golde te. FASEB J. 2000 Dec;14(15):2383-6. doi: 10.1096/fj.00-0286fje. FASEB J. 2000. PMID: 11024004
Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin.
Haugabook SJ, Le T, Yager D, Zenk B, Healy BM, Eckman EA, Prada C, Younkin L, Murphy P, Pinnix I, Onstead L, Sambamurti K, Golde TE, Dickson D, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: golde te. FASEB J. 2001 Jan;15(1):16-18. doi: 10.1096/fj.00-0528fje. Epub 2000 Nov 9. FASEB J. 2001. PMID: 11099491
Overexpression of nicastrin increases Abeta production.
Murphy MP, Das P, Nyborg AC, Rochette MJ, Dodson MW, Loosbrock NM, Souder TM, McLendon C, Merit SL, Piper SC, Jansen KR, Golde TE. Murphy MP, et al. Among authors: golde te. FASEB J. 2003 Jun;17(9):1138-40. doi: 10.1096/fj.02-1050fje. Epub 2003 Apr 8. FASEB J. 2003. PMID: 12692078
Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.
McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, DeLucia M, Lin WL, Dolios G, Wang R, Eckman CB, Dickson DW, Hutton M, Hardy J, Golde T. McGowan E, et al. Neuron. 2005 Jul 21;47(2):191-199. doi: 10.1016/j.neuron.2005.06.030. Neuron. 2005. PMID: 16039562 Free PMC article.
345 results