Smith FL - Search Results

1

Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice.

Gabra BH, Bailey CP, Kelly E, Smith FL, Henderson G, Dewey WL. Gabra BH, et al. Among authors: smith fl. Brain Res. 2008 Jun 27;1217:70-7. doi: 10.1016/j.brainres.2008.04.036. Epub 2008 Apr 24. Brain Res. 2008. PMID: 18501877 Free PMC article.

2

Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice.

Smith FL, Gabra BH, Smith PA, Redwood MC, Dewey WL. Smith FL, et al. Among authors: smith pa. Pain. 2007 Jan;127(1-2):129-39. doi: 10.1016/j.pain.2006.08.009. Epub 2006 Sep 11. Pain. 2007. PMID: 16965856

3

PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice.

Smith FL, Javed RR, Smith PA, Dewey WL, Gabra BH. Smith FL, et al. Among authors: smith pa. Pharmacol Res. 2006 Dec;54(6):474-80. doi: 10.1016/j.phrs.2006.09.007. Epub 2006 Sep 29. Pharmacol Res. 2006. PMID: 17056270

4

Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance.

Gabra BH, Bailey CP, Kelly E, Sanders AV, Henderson G, Smith FL, Dewey WL. Gabra BH, et al. Among authors: smith fl. Brain Res. 2007 Jul 23;1159:86-93. doi: 10.1016/j.brainres.2007.05.017. Epub 2007 May 21. Brain Res. 2007. PMID: 17582387 Free PMC article.

5

mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo.

Gabra BH, Smith FL, Navarro HA, Carroll FI, Dewey WL. Gabra BH, et al. Among authors: smith fl. Brain Res. 2008 Jan 2;1187:58-66. doi: 10.1016/j.brainres.2007.10.007. Epub 2007 Oct 12. Brain Res. 2008. PMID: 18022146 Free PMC article.

6

The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA.

Smith FL, Javed RR, Elzey MJ, Dewey WL. Smith FL, et al. Brain Res. 2003 Sep 19;985(1):78-88. doi: 10.1016/s0006-8993(03)03170-6. Brain Res. 2003. PMID: 12957370

7

Effects of mGlu1 and mGlu5 metabotropic glutamate antagonists to reverse morphine tolerance in mice.

Smith FL, Smith PA, Dewey WL, Javed RR. Smith FL, et al. Among authors: smith pa. Eur J Pharmacol. 2004 May 25;492(2-3):137-42. doi: 10.1016/j.ejphar.2004.03.055. Eur J Pharmacol. 2004. PMID: 15178357

8

PKC and PKA inhibitors reverse tolerance to morphine-induced hypothermia and supraspinal analgesia in mice.

Javed RR, Dewey WL, Smith PA, Smith FL. Javed RR, et al. Among authors: smith pa, smith fl. Eur J Pharmacol. 2004 May 25;492(2-3):149-57. doi: 10.1016/j.ejphar.2004.03.061. Eur J Pharmacol. 2004. PMID: 15178359

9

Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI).

Dalton GD, Smith FL, Smith PA, Dewey WL. Dalton GD, et al. Among authors: smith pa, smith fl. Neuropharmacology. 2005 Apr;48(5):648-57. doi: 10.1016/j.neuropharm.2004.12.006. Neuropharmacology. 2005. PMID: 15814100

10

Chronic Delta9-tetrahydrocannabinol treatment produces antinociceptive tolerance in mice without altering protein kinase A activity in mouse brain and spinal cord.

Dalton GD, Smith FL, Smith PA, Dewey WL. Dalton GD, et al. Among authors: smith pa, smith fl. Biochem Pharmacol. 2005 Jul 1;70(1):152-60. doi: 10.1016/j.bcp.2005.04.008. Biochem Pharmacol. 2005. PMID: 15913565

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