Wu G - Search Results

1

Structural requirements of chromokinesin Kif4A for its proper function in mitosis.

Wu G, Chen PL. Wu G, et al. Biochem Biophys Res Commun. 2008 Aug 1;372(3):454-8. doi: 10.1016/j.bbrc.2008.05.065. Epub 2008 May 23. Biochem Biophys Res Commun. 2008. PMID: 18502200

2

A novel role of the chromokinesin Kif4A in DNA damage response.

Wu G, Zhou L, Khidr L, Guo XE, Kim W, Lee YM, Krasieva T, Chen PL. Wu G, et al. Cell Cycle. 2008 Jul 1;7(13):2013-20. doi: 10.4161/cc.7.13.6130. Epub 2008 Apr 16. Cell Cycle. 2008. PMID: 18604178 Free PMC article.

3

Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal.

Wu G, Qiu XL, Zhou L, Zhu J, Chamberlin R, Lau J, Chen PL, Lee WH. Wu G, et al. Cancer Res. 2008 Oct 15;68(20):8393-9. doi: 10.1158/0008-5472.CAN-08-1915. Cancer Res. 2008. PMID: 18922912 Free PMC article.

4

A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia.

Zhu J, Zhou L, Wu G, Konig H, Lin X, Li G, Qiu XL, Chen CF, Hu CM, Goldblatt E, Bhatia R, Chamberlin AR, Chen PL, Lee WH. Zhu J, et al. Among authors: wu g. EMBO Mol Med. 2013 Mar;5(3):353-65. doi: 10.1002/emmm.201201760. Epub 2013 Jan 22. EMBO Mol Med. 2013. PMID: 23341130 Free PMC article.

5

Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues.

Qiu XL, Li G, Wu G, Zhu J, Zhou L, Chen PL, Chamberlin AR, Lee WH. Qiu XL, et al. Among authors: wu g. J Med Chem. 2009 Mar 26;52(6):1757-67. doi: 10.1021/jm8015969. J Med Chem. 2009. PMID: 19243176 Free PMC article.

6

Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1.

Wu G, Jiang X, Lee WH, Chen PL. Wu G, et al. Cancer Res. 2003 May 15;63(10):2589-95. Cancer Res. 2003. PMID: 12750284

7

Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1.

Wu G, Wei R, Cheng E, Ngo B, Lee WH. Wu G, et al. Mol Biol Cell. 2009 Nov;20(22):4686-95. doi: 10.1091/mbc.e08-11-1123. Epub 2009 Sep 23. Mol Biol Cell. 2009. PMID: 19776357 Free PMC article.

8

Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint.

Wei R, Ngo B, Wu G, Lee WH. Wei R, et al. Among authors: wu g. Mol Biol Cell. 2011 Oct;22(19):3584-94. doi: 10.1091/mbc.E11-01-0012. Epub 2011 Aug 10. Mol Biol Cell. 2011. PMID: 21832156 Free PMC article.

9

Hice1, a novel microtubule-associated protein required for maintenance of spindle integrity and chromosomal stability in human cells.

Wu G, Lin YT, Wei R, Chen Y, Shan Z, Lee WH. Wu G, et al. Mol Cell Biol. 2008 Jun;28(11):3652-62. doi: 10.1128/MCB.01923-07. Epub 2008 Mar 24. Mol Cell Biol. 2008. PMID: 18362163 Free PMC article.

10

RINT-1 serves as a tumor suppressor and maintains Golgi dynamics and centrosome integrity for cell survival.

Lin X, Liu CC, Gao Q, Zhang X, Wu G, Lee WH. Lin X, et al. Among authors: wu g. Mol Cell Biol. 2007 Jul;27(13):4905-16. doi: 10.1128/MCB.02396-06. Epub 2007 Apr 30. Mol Cell Biol. 2007. PMID: 17470549 Free PMC article.

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