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Page 1
In vitro activity of ferroquine is independent of polymorphisms in transport protein genes implicated in quinoline resistance in Plasmodium falciparum.
Henry M, Briolant S, Fontaine A, Mosnier J, Baret E, Amalvict R, Fusaï T, Fraisse L, Rogier C, Pradines B. Henry M, et al. Among authors: fraisse l. Antimicrob Agents Chemother. 2008 Aug;52(8):2755-9. doi: 10.1128/AAC.00060-08. Epub 2008 May 27. Antimicrob Agents Chemother. 2008. PMID: 18505855 Free PMC article.
In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum.
Daher W, Pelinski L, Klieber S, Sadoun F, Meunier V, Bourrié M, Biot C, Guillou F, Fabre G, Brocard J, Fraisse L, Maffrand JP, Khalife J, Dive D. Daher W, et al. Among authors: fraisse l. Drug Metab Dispos. 2006 Apr;34(4):667-82. doi: 10.1124/dmd.104.003202. Epub 2006 Jan 13. Drug Metab Dispos. 2006. PMID: 16415117
The antimalarial ferroquine: from bench to clinic.
Biot C, Nosten F, Fraisse L, Ter-Minassian D, Khalife J, Dive D. Biot C, et al. Among authors: fraisse l. Parasite. 2011 Aug;18(3):207-14. doi: 10.1051/parasite/2011183207. Parasite. 2011. PMID: 21894260 Free PMC article. Review.
Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate.
Wein S, Maynadier M, Bordat Y, Perez J, Maheshwari S, Bette-Bobillo P, Tran Van Ba C, Penarete-Vargas D, Fraisse L, Cerdan R, Vial H. Wein S, et al. Among authors: fraisse l. Br J Pharmacol. 2012 Aug;166(8):2263-76. doi: 10.1111/j.1476-5381.2012.01966.x. Br J Pharmacol. 2012. PMID: 22471905 Free PMC article.
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance.
Murithi JM, Pascal C, Bath J, Boulenc X, Gnädig NF, Pasaje CFA, Rubiano K, Yeo T, Mok S, Klieber S, Desert P, Jiménez-Díaz MB, Marfurt J, Rouillier M, Cherkaoui-Rbati MH, Gobeau N, Wittlin S, Uhlemann AC, Price RN, Wirjanata G, Noviyanti R, Tumwebaze P, Cooper RA, Rosenthal PJ, Sanz LM, Gamo FJ, Joseph J, Singh S, Bashyam S, Augereau JM, Giraud E, Bozec T, Vermat T, Tuffal G, Guillon JM, Menegotto J, Sallé L, Louit G, Cabanis MJ, Nicolas MF, Doubovetzky M, Merino R, Bessila N, Angulo-Barturen I, Baud D, Bebrevska L, Escudié F, Niles JC, Blasco B, Campbell S, Courtemanche G, Fraisse L, Pellet A, Fidock DA, Leroy D. Murithi JM, et al. Among authors: fraisse l. Sci Transl Med. 2021 Jul 21;13(603):eabg6013. doi: 10.1126/scitranslmed.abg6013. Sci Transl Med. 2021. PMID: 34290058 Free PMC article.
49 results