Bethke TD - Search Results

1

Single-dose pharmacokinetics of roflumilast in children and adolescents.

Neville KA, Szefler SJ, Abdel-Rahman SM, Lahu G, Zech K, Herzog R, Bethke TD, Gleason MC, Kearns GL. Neville KA, et al. Among authors: bethke td. J Clin Pharmacol. 2008 Aug;48(8):978-85. doi: 10.1177/0091270008319466. Epub 2008 May 28. J Clin Pharmacol. 2008. PMID: 18508947 Clinical Trial.

2

High absolute bioavailability of the new oral phosphodiesterase-4 inhibitor roflumilast.

Bethke TD, Lahu G. Bethke TD, et al. Int J Clin Pharmacol Ther. 2011 Jan;49(1):51-7. doi: 10.5414/cpp49051. Int J Clin Pharmacol Ther. 2011. PMID: 21176727 Clinical Trial.

3

Lack of pharmacokinetic and pharmacodynamic interactions of roflumilast with (R, S)-warfarin in healthy adult subjects.

McCracken N, Lahu G, Bethke TD. McCracken N, et al. Among authors: bethke td. Int J Clin Pharmacol Ther. 2011 Jun;49(6):388-96. doi: 10.5414/cp201523. Int J Clin Pharmacol Ther. 2011. PMID: 21612746 Clinical Trial.

4

Investigation of a potential food effect on the pharmacokinetics of roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor, in healthy subjects.

Hauns B, Hermann R, Hünnemeyer A, Herzog R, Hauschke D, Zech K, Bethke TD. Hauns B, et al. Among authors: bethke td. J Clin Pharmacol. 2006 Oct;46(10):1146-53. doi: 10.1177/0091270006291621. J Clin Pharmacol. 2006. PMID: 16988203 Clinical Trial.

5

The oral, once-daily phosphodiesterase 4 inhibitor roflumilast lacks relevant pharmacokinetic interactions with inhaled budesonide.

Hermann R, Siegmund W, Giessmann T, Westphal K, Weinbrenner A, Hauns B, Reutter F, Lahu G, Zech K, Bethke TD. Hermann R, et al. Among authors: bethke td. J Clin Pharmacol. 2007 Aug;47(8):1005-13. doi: 10.1177/0091270007300950. J Clin Pharmacol. 2007. PMID: 17660483 Clinical Trial.

6

Absence of pharmacokinetic interaction between roflumilast and digoxin in healthy adults.

Eckermann G, Lahu G, Nassr N, Bethke TD. Eckermann G, et al. Among authors: bethke td. J Clin Pharmacol. 2012 Feb;52(2):251-7. doi: 10.1177/0091270010389467. J Clin Pharmacol. 2012. PMID: 21257799 Clinical Trial.

7

Pharmacokinetic disposition of inhaled ciclesonide and its metabolite desisobutyryl-ciclesonide in healthy subjects and patients with asthma are similar.

Nave R, Gunawardena KA, Zech K, Bethke TD. Nave R, et al. Among authors: bethke td. Int J Clin Pharmacol Ther. 2006 Jan;44(1):1-7. doi: 10.5414/cpp44001. Int J Clin Pharmacol Ther. 2006. PMID: 16425964 Clinical Trial.

8

Roflumilast, a once-daily oral phosphodiesterase 4 inhibitor, lacks relevant pharmacokinetic interactions with inhaled salbutamol when co-administered in healthy subjects.

Bethke TD, Giessmann T, Westphal K, Weinbrenner A, Hauns B, Hauschke D, David M, Lahu G, Zech K, Hermann R, Siegmund W. Bethke TD, et al. Int J Clin Pharmacol Ther. 2006 Nov;44(11):572-9. doi: 10.5414/cpp44572. Int J Clin Pharmacol Ther. 2006. PMID: 17176624 Clinical Trial.

9

Study investigating pharmacokinetic interaction between theophylline and roflumilast in healthy adults.

Böhmer G, Gleiter CH, Hünnemeyer A, Lahu G, Bethke TD. Böhmer G, et al. Among authors: bethke td. Int J Clin Pharmacol Ther. 2011 Jul;49(7):451-60. doi: 10.5414/cp201535. Int J Clin Pharmacol Ther. 2011. PMID: 21726496 Clinical Trial.

10

Influence of renal impairment on the pharmacokinetics of oral roflumilast: an open-label, parallel-group, single-center study.

Bethke TD, Hartmann M, Hünnemeyer A, Lahu G, Gleiter CH. Bethke TD, et al. Int J Clin Pharmacol Ther. 2011 Aug;49(8):491-9. doi: 10.5414/cp201556. Int J Clin Pharmacol Ther. 2011. PMID: 21781649 Clinical Trial.

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