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AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers.
Belmontes B, Slemmons KK, Su C, Liu S, Policheni AN, Moriguchi J, Tan H, Xie F, Aiello DA, Yang Y, Lazaro R, Aeffner F, Rees MG, Ronan MM, Roth JA, Vestergaard M, Cowland S, Andersson J, Sarvary I, Chen Q, Sharma P, Lopez P, Tamayo N, Pettus LH, Ghimire-Rijal S, Mukund S, Allen JR, DeVoss J, Coxon A, Rodon J, Ghiringhelli F, Penel N, Prenen H, Glad S, Chuang CH, Keyvanjah K, Townsley DM, Butler JR, Bourbeau MP, Caenepeel S, Hughes PE. Belmontes B, et al. Among authors: moriguchi j. Cancer Discov. 2025 Jan 13;15(1):139-161. doi: 10.1158/2159-8290.CD-24-0887. Cancer Discov. 2025. PMID: 39282709 Free PMC article.
Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers.
Payton M, Belmontes B, Hanestad K, Moriguchi J, Chen K, McCarter JD, Chung G, Ninniri MS, Sun J, Manoukian R, Chambers S, Ho SM, Kurzeja RJM, Edson KZ, Dahal UP, Wu T, Wannberg S, Beltran PJ, Canon J, Boghossian AS, Rees MG, Ronan MM, Roth JA, Minocherhomji S, Bourbeau MP, Allen JR, Coxon A, Tamayo NA, Hughes PE. Payton M, et al. Among authors: moriguchi j. Nat Cancer. 2024 Jan;5(1):66-84. doi: 10.1038/s43018-023-00699-5. Epub 2023 Dec 27. Nat Cancer. 2024. PMID: 38151625 Free PMC article.
[A survey of research activity challenges among occupational health practitioners].
Fukai K, Song YH, Moriguchi J, Watai I, Yoshita K, Fukuda M, Hara K, Tsutsumi A. Fukai K, et al. Among authors: moriguchi j. Sangyo Eiseigaku Zasshi. 2024 May 25;66(3):128-133. doi: 10.1539/sangyoeisei.2023-031-S. Epub 2023 Dec 15. Sangyo Eiseigaku Zasshi. 2024. PMID: 38104980 Free article. Japanese. No abstract available.
215 results