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Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area.
Mátyás F, Urbán GM, Watanabe M, Mackie K, Zimmer A, Freund TF, Katona I. Mátyás F, et al. Among authors: zimmer a. Neuropharmacology. 2008 Jan;54(1):95-107. doi: 10.1016/j.neuropharm.2007.05.028. Epub 2007 Jun 22. Neuropharmacology. 2008. PMID: 17655884 Free PMC article.
Attenuation of allergic contact dermatitis through the endocannabinoid system.
Karsak M, Gaffal E, Date R, Wang-Eckhardt L, Rehnelt J, Petrosino S, Starowicz K, Steuder R, Schlicker E, Cravatt B, Mechoulam R, Buettner R, Werner S, Di Marzo V, Tüting T, Zimmer A. Karsak M, et al. Among authors: zimmer a. Science. 2007 Jun 8;316(5830):1494-7. doi: 10.1126/science.1142265. Science. 2007. PMID: 17556587
Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia.
Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL 2nd, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG. Gregg LC, et al. Among authors: zimmer a. J Neurosci. 2012 Jul 11;32(28):9457-68. doi: 10.1523/JNEUROSCI.0013-12.2012. J Neurosci. 2012. PMID: 22787031 Free PMC article.
Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment.
Murikinati S, Jüttler E, Keinert T, Ridder DA, Muhammad S, Waibler Z, Ledent C, Zimmer A, Kalinke U, Schwaninger M. Murikinati S, et al. Among authors: zimmer a. FASEB J. 2010 Mar;24(3):788-98. doi: 10.1096/fj.09-141275. Epub 2009 Nov 2. FASEB J. 2010. PMID: 19884325
However, the mechanisms underlying this protective action are unclear. In a mouse model of ischemic stroke, we show that the CB(2) agonist JWH-133 (1 mg . kg(-1) . d(-1)) decreases the infarct size measured 3 d after onset of ischemia. ...-Murikinati, S., Juttler, E., Kein …
However, the mechanisms underlying this protective action are unclear. In a mouse model of ischemic stroke, we show that the CB(2) ag …
986 results