Kirk BE - Search Results

1

X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain.

Biggadike K, Bledsoe RK, Hassell AM, Kirk BE, McLay IM, Shewchuk LM, Stewart EL. Biggadike K, et al. Among authors: kirk be. J Med Chem. 2008 Jun 26;51(12):3349-52. doi: 10.1021/jm800279t. Epub 2008 Jun 4. J Med Chem. 2008. PMID: 18522385

2

Fluoro carbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluoro carbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil.

Borthwick AD, Evans DN, Kirk BE, Biggadike K, Exall AM, Youds P, Roberts SM, Knight DJ, Coates JA. Borthwick AD, et al. Among authors: kirk be. J Med Chem. 1990 Jan;33(1):179-86. doi: 10.1021/jm00163a030. J Med Chem. 1990. PMID: 2153201

3

Fluorocarbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxy guanosines.

Borthwick AD, Kirk BE, Biggadike K, Exall AM, Butt S, Roberts SM, Knight DJ, Coates JA, Ryan DM. Borthwick AD, et al. Among authors: kirk be. J Med Chem. 1991 Mar;34(3):907-14. doi: 10.1021/jm00107a006. J Med Chem. 1991. PMID: 1848298

4

The squalestatins: synthesis and biological activity of some C3-modified analogues; replacement of a carboxylic acid or methyl ester with an isoelectronic heterocyclic functionality.

Bamford MJ, Chan C, Craven AP, Dymock BW, Green D, Henson RA, Kirk BE, Lester MG, Procopiou PA, Snowden MA, et al. Bamford MJ, et al. Among authors: kirk be. J Med Chem. 1995 Sep 1;38(18):3502-13. doi: 10.1021/jm00018a010. J Med Chem. 1995. PMID: 7658437

5

The squalestatins: novel inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C1-modified analogues.

Procopiou PA, Bailey EJ, Bamford MJ, Craven AP, Dymock BW, Houston JG, Hutson JL, Kirk BE, McCarthy AD, Sareen M, et al. Procopiou PA, et al. Among authors: kirk be. J Med Chem. 1994 Sep 30;37(20):3274-81. doi: 10.1021/jm00046a011. J Med Chem. 1994. PMID: 7932554

6

Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors.

Chan C, Bailey EJ, Hartley CD, Hayman DF, Hutson JL, Inglis GG, Jones PS, Keeling SE, Kirk BE, Lamont RB, et al. Chan C, et al. Among authors: kirk be. J Med Chem. 1993 Nov 12;36(23):3646-57. doi: 10.1021/jm00075a020. J Med Chem. 1993. PMID: 8246233

7

The squalestatins: inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C3-modified analogues.

Procopiou PA, Cox B, Kirk BE, Lester MG, McCarthy AD, Sareen M, Sharratt PJ, Snowden MA, Spooner SJ, Watson NS, Widdowson J. Procopiou PA, et al. Among authors: kirk be. J Med Chem. 1996 Mar 29;39(7):1413-22. doi: 10.1021/jm950893j. J Med Chem. 1996. PMID: 8691471

8

Mycoplasma-induced hydrocephalus in rats and hamsters.

Kohn DF, Kirk BE, Chou SM. Kohn DF, et al. Among authors: kirk be. Infect Immun. 1977 May;16(2):680-9. doi: 10.1128/iai.16.2.680-689.1977. Infect Immun. 1977. PMID: 558963 Free PMC article.

9

Analysis of baby hamster kidney cells persistently infected with lymphocytic choriomeningitis virus.

Stanwick TL, Kirk BE. Stanwick TL, et al. Among authors: kirk be. J Gen Virol. 1976 Sep;32(3):361-7. doi: 10.1099/0022-1317-32-3-361. J Gen Virol. 1976. PMID: 987157

10

Neutralizing antibody response of guinea pigs to lymphocytic choriomeningitis virus.

Webster JM, Kirk BE. Webster JM, et al. Among authors: kirk be. Infect Immun. 1974 Sep;10(3):516-9. doi: 10.1128/iai.10.3.516-519.1974. Infect Immun. 1974. PMID: 4609904 Free PMC article.

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