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Page 1
Cyclic urea derivatives as potent NK1 selective antagonists.
Shue HJ, Chen X, Shih NY, Blythin DJ, Paliwal S, Lin L, Gu D, Schwerdt JH, Shah S, Reichard GA, Piwinski JJ, Duffy RA, Lachowicz JE, Coffin VL, Liu F, Nomeir AA, Morgan CA, Varty GB. Shue HJ, et al. Among authors: reichard ga. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3896-9. doi: 10.1016/j.bmcl.2005.05.111. Bioorg Med Chem Lett. 2005. PMID: 16019209
Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions.
Shue HJ, Chen X, Schwerdt JH, Paliwal S, Blythin DJ, Lin L, Gu D, Wang C, Reichard GA, Wang H, Piwinski JJ, Duffy RA, Lachowicz JE, Coffin VL, Nomeir AA, Morgan CA, Varty GB, Shih NY. Shue HJ, et al. Among authors: reichard ga. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1065-9. doi: 10.1016/j.bmcl.2005.10.072. Epub 2005 Nov 14. Bioorg Med Chem Lett. 2006. PMID: 16290143
Cyclobutane derivatives as potent NK1 selective antagonists.
Wrobleski ML, Reichard GA, Paliwal S, Shah S, Tsui HC, Duffy RA, Lachowicz JE, Morgan CA, Varty GB, Shih NY. Wrobleski ML, et al. Among authors: reichard ga. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3859-63. doi: 10.1016/j.bmcl.2006.04.031. Epub 2006 May 8. Bioorg Med Chem Lett. 2006. PMID: 16682196
The design and synthesis of novel NK1/NK2 dual antagonists.
Reichard GA, Ball ZT, Aslanian R, Anthes JC, Shih NY, Piwinski JJ. Reichard GA, et al. Bioorg Med Chem Lett. 2000 Oct 16;10(20):2329-32. doi: 10.1016/s0960-894x(00)00463-7. Bioorg Med Chem Lett. 2000. PMID: 11055349
SCH 206272: a potent, orally active tachykinin NK(1), NK(2), and NK(3) receptor antagonist.
Anthes JC, Chapman RW, Richard C, Eckel S, Corboz M, Hey JA, Fernandez X, Greenfeder S, McLeod R, Sehring S, Rizzo C, Crawley Y, Shih NY, Piwinski J, Reichard G, Ting P, Carruthers N, Cuss FM, Billah M, Kreutner W, Egan RW. Anthes JC, et al. Eur J Pharmacol. 2002 Aug 23;450(2):191-202. doi: 10.1016/s0014-2999(02)02124-6. Eur J Pharmacol. 2002. PMID: 12206858
82 results